用于筛板体内成像的自适应光学扫描激光检眼镜
Adaptive optics scanning laser ophthalmoscopy for in vivo imaging of lamina cribrosa.
作者信息
Vilupuru Abhiram S, Rangaswamy Nalini V, Frishman Laura J, Smith Earl L, Harwerth Ronald S, Roorda Austin
机构信息
College of Optometry, University of Houston, TX 77204-2020, USA.
出版信息
J Opt Soc Am A Opt Image Sci Vis. 2007 May;24(5):1417-25. doi: 10.1364/josaa.24.001417.
Abstract
The lamina cribrosa has been postulated from in vitro studies as an early site of damage in glaucoma. Prior in vivo measures of laminar morphology have been confounded by ocular aberrations. In this study the lamina cribrosa was imaged after correcting for ocular aberrations using the adaptive optics scanning laser ophthalmoscope (AOSLO) in normal and glaucomatous eyes of rhesus monkeys. All measured laminar morphological parameters showed increased magnitudes in glaucomatous eyes relative to fellow control eyes, indicating altered structure. The AOSLO provides high-quality images of the lamina cribrosa and may have potential as a tool for early identification of glaucoma.
摘要
从体外研究推测，筛板是青光眼早期损伤的部位。先前对板层形态的体内测量因眼像差而受到干扰。在本研究中，使用自适应光学扫描激光检眼镜（AOSLO）校正眼像差后，对恒河猴正常眼和青光眼眼中的筛板进行成像。所有测量的板层形态学参数显示，青光眼眼相对于对侧对照眼的数值增加，表明结构发生了改变。AOSLO能提供高质量的筛板图像，可能具有作为早期青光眼识别工具的潜力。
相似文献
1
Adaptive optics scanning laser ophthalmoscopy for in vivo imaging of lamina cribrosa.用于筛板体内成像的自适应光学扫描激光检眼镜
J Opt Soc Am A Opt Image Sci Vis. 2007 May;24(5):1417-25. doi: 10.1364/josaa.24.001417.
2
Deformation of the lamina cribrosa and anterior scleral canal wall in early experimental glaucoma.早期实验性青光眼中筛板和前巩膜管管壁的变形
Invest Ophthalmol Vis Sci. 2003 Feb;44(2):623-37. doi: 10.1167/iovs.01-1282.
3
In vivo imaging of lamina cribrosa pores by adaptive optics scanning laser ophthalmoscopy.自适应光学扫描激光检眼镜对神经纤维层筛板孔的活体成像。
Invest Ophthalmol Vis Sci. 2012 Jun 26;53(7):4111-9. doi: 10.1167/iovs.11-7536.
4
In vivo morphometry of the lamina cribrosa and its relation to visual field loss in glaucoma.
Curr Eye Res. 1998 Apr;17(4):363-9. doi: 10.1080/02713689808951216.
5
Thickness of the lamina cribrosa and peripapillary sclera in Rhesus monkeys with nonglaucomatous or glaucomatous optic neuropathy.正常眼压性或青光眼性视神经病变的猕猴的神经节细胞层和视盘周围巩膜厚度。
Acta Ophthalmol. 2011 Aug;89(5):e423-7. doi: 10.1111/j.1755-3768.2011.02121.x. Epub 2011 Feb 18.
6
Reproducibility of measuring lamina cribrosa pore geometry in human and nonhuman primates with in vivo adaptive optics imaging.利用活体自适应光学成像技术测量人类和非人类灵长类动物视乳头筛板孔几何形状的可重复性。
Invest Ophthalmol Vis Sci. 2011 Jul 23;52(8):5473-80. doi: 10.1167/iovs.11-7347.
7
3-D histomorphometry of the normal and early glaucomatous monkey optic nerve head: lamina cribrosa and peripapillary scleral position and thickness.正常及早期青光眼猴视神经乳头的三维组织形态计量学：筛板及视乳头周围巩膜的位置和厚度
Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4597-607. doi: 10.1167/iovs.07-0349.
8
[Morphometric features in the lamina cribrosa observed by a scanning laser ophthalmoscope].
Nippon Ganka Gakkai Zasshi. 1999 Jan;103(1):48-55.
9
In Vivo Changes in Lamina Cribrosa Microarchitecture and Optic Nerve Head Structure in Early Experimental Glaucoma.早期实验性青光眼中筛板微结构和视神经乳头结构的体内变化
PLoS One. 2015 Jul 31;10(7):e0134223. doi: 10.1371/journal.pone.0134223. eCollection 2015.
10
Remodeling of the connective tissue microarchitecture of the lamina cribrosa in early experimental glaucoma.早期实验性青光眼筛板结缔组织微结构的重塑
Invest Ophthalmol Vis Sci. 2009 Feb;50(2):681-90. doi: 10.1167/iovs.08-1792. Epub 2008 Sep 20.
引用本文的文献
1
Lamina Cribrosa Microstructure in Nonhuman Primates With Naturally Occurring Peripapillary Retinal Nerve Fiber Layer Thinning.非人类灵长类动物自然发生的视盘周围视网膜神经纤维层变薄的视盘筛板微观结构。
Transl Vis Sci Technol. 2024 Sep 3;13(9):23. doi: 10.1167/tvst.13.9.23.
2
Clinical Application of Adaptive Optics Imaging in Diagnosis, Management, and Monitoring of Ophthalmological Diseases: A Narrative Review.自适应光学成像在眼科疾病的诊断、治疗和监测中的临床应用：叙述性综述。
Med Sci Monit. 2023 Dec 4;29:e941926. doi: 10.12659/MSM.941926.
3
Quantitative Microstructural Analysis of Cellular and Tissue Remodeling in Human Glaucoma Optic Nerve Head.人青光眼视神经头细胞和组织重塑的定量微观结构分析。
Invest Ophthalmol Vis Sci. 2022 Oct 3;63(11):18. doi: 10.1167/iovs.63.11.18.
4
Optical Coherence Tomography and Glaucoma.光学相干断层扫描与青光眼。
Annu Rev Vis Sci. 2021 Sep 15;7:693-726. doi: 10.1146/annurev-vision-100419-111350. Epub 2021 Jul 9.
5
Optical Coherence Tomography Imaging of the Lamina Cribrosa: Structural Biomarkers in Nonglaucomatous Diseases.筛板的光学相干断层扫描成像：非青光眼性疾病中的结构生物标志物
J Ophthalmol. 2021 Feb 19;2021:8844614. doi: 10.1155/2021/8844614. eCollection 2021.
6
Discovery and clinical translation of novel glaucoma biomarkers.新型青光眼生物标志物的发现与临床转化。
Prog Retin Eye Res. 2021 Jan;80:100875. doi: 10.1016/j.preteyeres.2020.100875. Epub 2020 Jul 10.
7
Relationship between Progressive Changes in Lamina Cribrosa Depth and Deterioration of Visual Field Loss in Glaucomatous Eyes.青光眼患者筛板深度的渐进性变化与视野缺损恶化之间的关系。
Korean J Ophthalmol. 2018 Dec;32(6):470-477. doi: 10.3341/kjo.2018.0015.
8
In vivo analysis of glaucoma-related features within the optic nerve head using enhanced depth imaging optical coherence tomography.使用增强深度成像光学相干断层扫描对视神经头内青光眼相关特征进行体内分析。
PLoS One. 2017 Jul 21;12(7):e0180128. doi: 10.1371/journal.pone.0180128. eCollection 2017.
9
Adaptive optics optical coherence tomography in glaucoma.青光眼的自适应光学光学相干断层扫描
Prog Retin Eye Res. 2017 Mar;57:76-88. doi: 10.1016/j.preteyeres.2016.11.001. Epub 2016 Dec 1.
10
Adaptive optics ophthalmoscopy.自适应光学检眼镜检查法
Annu Rev Vis Sci. 2015 Nov;1:19-50. doi: 10.1146/annurev-vision-082114-035357. Epub 2015 Oct 14.
本文引用的文献
1
Hypothesis concerning the pathophysiology of optic nerve damage in open angle glaucoma.关于开角型青光眼视神经损伤病理生理学的假说。
J Glaucoma. 1993 Summer;2(2):119-27.
2
Adaptive optics scanning laser ophthalmoscopy.自适应光学扫描激光检眼镜
Opt Express. 2002 May 6;10(9):405-12. doi: 10.1364/oe.10.000405.
3
Direct and noninvasive assessment of parafoveal capillary leukocyte velocity.黄斑旁毛细血管白细胞速度的直接和非侵入性评估。
Ophthalmology. 2005 Dec;112(12):2219-24. doi: 10.1016/j.ophtha.2005.06.033. Epub 2005 Oct 27.
4
Factors influencing optic nerve head biomechanics.影响视神经乳头生物力学的因素。
Invest Ophthalmol Vis Sci. 2005 Nov;46(11):4189-99. doi: 10.1167/iovs.05-0541.
5
Dynamic visual stimulus presentation in an adaptive optics scanning laser ophthalmoscope.自适应光学扫描激光检眼镜中的动态视觉刺激呈现
J Refract Surg. 2005 Sep-Oct;21(5):S575-80. doi: 10.3928/1081-597X-20050901-30.
6
Optical slicing of human retinal tissue in vivo with the adaptive optics scanning laser ophthalmoscope.使用自适应光学扫描激光检眼镜对人视网膜组织进行体内光学切片。
Appl Opt. 2005 Jul 1;44(19):4032-40. doi: 10.1364/ao.44.004032.
7
Viscoelastic material properties of the peripapillary sclera in normal and early-glaucoma monkey eyes.正常和早期青光眼猴眼视乳头周围巩膜的粘弹性材料特性
Invest Ophthalmol Vis Sci. 2005 Feb;46(2):540-6. doi: 10.1167/iovs.04-0114.
8
The optic nerve head as a biomechanical structure: a new paradigm for understanding the role of IOP-related stress and strain in the pathophysiology of glaucomatous optic nerve head damage.作为生物力学结构的视神经乳头：理解眼内压相关应力和应变在青光眼性视神经乳头损害病理生理学中作用的新范式。
Prog Retin Eye Res. 2005 Jan;24(1):39-73. doi: 10.1016/j.preteyeres.2004.06.001.
9
Three dimensional analysis of the lamina cribrosa in glaucoma.青光眼筛板的三维分析
Br J Ophthalmol. 2004 Oct;88(10):1299-304. doi: 10.1136/bjo.2003.036020.
10
Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, II: Structural measures.美金刚治疗对减轻猴实验性青光眼相关变化的疗效和安全性，II：结构测量
Invest Ophthalmol Vis Sci. 2004 Aug;45(8):2640-51. doi: 10.1167/iovs.03-0567.
Zotero 插件