Stoimenova Bistra D
Department of Physiology, Medical University Sofia, Sofia, Bulgaria.
Invest Ophthalmol Vis Sci. 2007 May;48(5):2371-4. doi: 10.1167/iovs.05-1377.
To examine the relationship between the degree of myopia and foveally measured contrast thresholds.
Monocular thresholds for positive and negative contrast were obtained from 60 myopes (-1.0 to -8.0 D) and 20 emmetropes of similar age. The contrast thresholds were measured at different background luminance levels, photopic and mesopic, by using a visual stimulus generator and a staircase
Against a gray background, light (dark) letters were used to study positive (negative) contrast. ANOVA was used to identify factors influencing the contrast sensitivity. For the myopes, the contrast thresholds were regressed against the spherical equivalent refractive error, accounting for different intercepts and slopes between positive and negative contrasts.
Myopes yielded lower sensitivity to contrast than did emmetropes and, in contrast to emmetropes, exhibited higher contrast thresholds for negative than for positive contrast in both photopic and mesopic conditions. At all background luminance levels, contrast thresholds of myopic subjects increased systematically with a higher spherical equivalent refractive error, and the rate of increase was higher for negative than for positive contrast. The regression models yielded adjusted coefficients of determination (R(2)(adj)) of 0.735 and higher.
Despite having corrected visual acuity, myopes exhibited reduced sensitivity to contrast in comparison to emmetropes. Furthermore, the contrast sensitivity decreased with an increasing degree of myopia, and the rate of decline was higher for negative than for positive contrast.
研究近视程度与中央凹测量的对比度阈值之间的关系。
从60名近视患者(-1.0至-8.0 D)和20名年龄相仿的正视眼中获得单眼正、负对比度阈值。通过使用视觉刺激发生器和阶梯法,在不同背景亮度水平(明视觉和中间视觉)下测量对比度阈值。
以灰色背景为对照,使用亮(暗)字母研究正(负)对比度。采用方差分析来确定影响对比度敏感性的因素。对于近视患者,将对比度阈值与等效球镜屈光不正进行回归分析,同时考虑正、负对比度之间不同的截距和斜率。
与正视眼相比,近视患者对对比度的敏感性较低,并且与正视眼不同的是,在明视觉和中间视觉条件下,近视患者的负对比度阈值均高于正对比度阈值。在所有背景亮度水平下,近视患者的对比度阈值均随等效球镜屈光不正的增加而系统性升高,且负对比度的升高速率高于正对比度。回归模型得出的调整决定系数(R(2)(adj))为0.735及更高。
尽管近视患者的视力已矫正,但与正视眼相比,他们对对比度的敏感性仍降低。此外,对比度敏感性随近视程度的增加而降低,且负对比度的下降速率高于正对比度。