Lauwers S, Philippe J, Van Zeebroeck A, Pierard D, Derde M P, Kaufman L
Department of Microbiology, Free University of Brussels, Belgium.
Eur J Clin Microbiol Infect Dis. 1991 Aug;10(8):652-6. doi: 10.1007/BF01975819.
A Belgian multicenter trial was conducted to evaluate problems encountered with quality control results of antimicrobial disk susceptibility testing and to compare the performance of BBL disks and Rosco tablets. Over a period of four weeks 18 laboratories daily tested three reference strains against eight antibiotics. A standardised method was used by all participants. For all results together 10.4% and 7.3% of the measurements with BBL disks and Rosco tablets, respectively, were outside the recommended range. Major problems were observed for some specific strain-antibiotic combinations. Standard deviations were similar for both systems; their precision was comparable. The results suggest that cooperation between manufacturers and some reference laboratories could be improved in order to establish optimal quality control limits.
比利时开展了一项多中心试验，以评估抗菌药敏纸片扩散法质量控制结果中遇到的问题，并比较BBL药敏纸片和罗斯科药敏片的性能。在四周的时间里，18个实验室每天针对8种抗生素对3种参考菌株进行检测。所有参与者都使用了标准化方法。总体而言，使用BBL药敏纸片和罗斯科药敏片测得的结果分别有10.4%和7.3%超出了推荐范围。在某些特定的菌株 - 抗生素组合中观察到了主要问题。两个系统的标准差相似；它们的精密度相当。结果表明，制造商与一些参考实验室之间的合作有待改进，以便确定最佳的质量控制限度。
