Peraza-Sánchez S R, Cen-Pacheco F, Noh-Chimal A, May-Pat F, Simá-Polanco P, Dumonteil E, García-Miss M R, Mut-Martín M
Centro de Investigación Científica de Yucatán, Calle 41 #130, Col. Chuburná de Hidalgo, Merida, Yucatan, 97200 (CICY), Mexico.
Fitoterapia. 2007 Jun;78(4):315-8. doi: 10.1016/j.fitote.2007.03.013. Epub 2007 Apr 11.
Methanol extracts were prepared from different parts of 18 plants collected in the Yucatan peninsula and evaluated in an in vitro bioassay for leishmanicidal activity against Leishmania mexicana promastigotes. The ten most potent plant extracts (IC(50)<50 microg/ml) were Aphelandra scabra leaves, Byrsonima bucidaefolia bark, Byrsonima crassifolia bark, Clusia flava leaves, Cupania dentata bark, Diphysa carthagenensis leaves, Dorstenia contrajerva whole plant, Milleria quinqueflora roots, Tridax procumbens whole plant, and Vitex gaumeri bark.
从尤卡坦半岛采集的18种植物的不同部位制备了甲醇提取物，并在体外生物测定中评估了其对墨西哥利什曼原虫前鞭毛体的杀利什曼活性。十种最有效的植物提取物（IC(50)<50微克/毫升）分别是虾衣花叶子、布氏叶下珠树皮、厚叶叶下珠树皮、黄藤黄叶子、具齿番荔枝树皮、卡氏双柱苏木叶子、多蕊麻整株植物、五蕊米勒草根部、平卧银胶菊整株植物和高氏牡荆树皮。
