Gallien P, Nicolas B, Robineau S, Pétrilli S, Houedakor J, Durufle A
Centre MPR, Notre-Dame-de-Lourdes, 54, rue Saint-Hélier, 35000 Rennes, France.
Ann Readapt Med Phys. 2007 Jul;50(6):373-6, 369-72. doi: 10.1016/j.annrmp.2007.04.004. Epub 2007 Apr 20.
For many years, patients with multiple sclerosis (MS) were advised to avoid exercise because of the risk of increased neurological impairment. This article reviews the literature related to MS and physical exercise. Physical exercise depends on patients' physiological tolerance and response to exercise. MS patients can exhibit dysfunction of cardiovascular adjustment accompanied by respiratory involvement, which can alter aerobic capacity. These abnormalities tend to increase with the neurological impairment. Muscle weakness is the consequence of not only altered central motor drive but also disuse. Several studies have shown the benefits of physical training, with improvements in aerobic capacity, gait parameters and fatigue, and an influence on quality of life. Regular aerobic physical activity is necessary to maintain the benefit of physical training.
多年来，由于存在神经功能障碍加重的风险，多发性硬化症（MS）患者一直被建议避免运动。本文回顾了与MS和体育锻炼相关的文献。体育锻炼取决于患者的生理耐受性和对运动的反应。MS患者可能会出现心血管调节功能障碍并伴有呼吸受累，这会改变有氧运动能力。这些异常往往会随着神经功能障碍而增加。肌肉无力不仅是中枢运动驱动改变的结果，也是废用的结果。多项研究表明体育锻炼有益，可改善有氧运动能力、步态参数和疲劳，并对生活质量产生影响。定期进行有氧体育活动对于维持体育锻炼的益处是必要的。
