集胞藻PCC 7120中异形胞包膜多糖形成所需的预测糖基转移酶基因位于HEP岛之外。
Predicted glycosyl transferase genes located outside the HEP island are required for formation of heterocyst envelope polysaccharide in Anabaena sp. strain PCC 7120.
作者信息
Wang Yu, Lechno-Yossef Sigal, Gong Yangmin, Fan Qing, Wolk C Peter, Xu Xudong
机构信息
The State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei 430072, People's Republic of China.
出版信息
J Bacteriol. 2007 Jul;189(14):5372-8. doi: 10.1128/JB.00343-07. Epub 2007 May 4.
Abstract
During maturation, heterocysts form an envelope layer of polysaccharide, called heterocyst envelope polysaccharide (HEP), whose synthesis depends on a cluster of genes, the HEP island, and on an additional, distant gene, hepB, or a gene immediately downstream from hepB. We show that HEP formation depends upon the predicted glycosyl transferase genes all4160 at a third locus and alr3699, which is adjacent to hepB and is cotranscribed with it. Mutations in the histidine kinase genes hepN and hepK appear to silence the promoter of hepB and incompletely down-regulate all4160.
摘要
在成熟过程中，异形胞形成一层多糖包膜，称为异形胞包膜多糖（HEP），其合成依赖于一组基因，即HEP岛，以及另一个距离较远的基因hepB，或hepB下游紧邻的一个基因。我们发现，HEP的形成依赖于位于第三个位点的预测糖基转移酶基因all4160和与hepB相邻并与其共转录的alr3699。组氨酸激酶基因hepN和hepK中的突变似乎会使hepB的启动子沉默，并不能完全下调all4160。
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