巨细胞病毒感染中的平滑肌抗体及其他组织抗体
Smooth-muscle antibodies and other tissue antibodies in cytomegalovirus infection.
作者信息
Andersen P, Andersen H K
出版信息
Clin Exp Immunol. 1975 Oct;22(1):22-9.
Abstract
Smooth-muscle antibodies (SMA) were present in 16% of sixty-three patients with cytomegalovirus (CMV) antibodies in serum and absent in forty CMV antibody-negative blood donors (P = 0-005). The SMA were of the IgG and IgM class, while no IgA antibodies were found. In patients with CMV infection, SMA, mainly of the IgM class, were present in the early stages of the disease, and the titre decreased faster than the complement-fixing CMV antibody titre. Anti-nuclear antibodies (ANA) were also found more often in CMV antibody-positive sera than in CMV antibody-negative sera, and ANA were usually present in sera which also contained SMA. Parietal cell antibodies, mitochondrial antibodies and other cytoplasmic antibodies did not occur more frequently in CMV antibody-positive than in CMV antibody-negative sera.
摘要
在63例血清中存在巨细胞病毒（CMV）抗体的患者中，16%存在平滑肌抗体（SMA），而40例CMV抗体阴性的献血者中未发现SMA（P = 0.005）。SMA属于IgG和IgM类，未发现IgA抗体。在CMV感染患者中，SMA主要为IgM类，在疾病早期出现，其滴度下降速度比补体结合CMV抗体滴度更快。抗核抗体（ANA）在CMV抗体阳性血清中也比在CMV抗体阴性血清中更常见，且ANA通常存在于同时含有SMA的血清中。壁细胞抗体、线粒体抗体和其他细胞质抗体在CMV抗体阳性血清中出现的频率并不比CMV抗体阴性血清更高。
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