传染性单核细胞增多症中的平滑肌自身抗体。
Smooth muscle autoantibodies in infectious mononucleosis.
作者信息
Holborow E J, Hemsted E H, Mead S V
出版信息
Br Med J. 1973 Aug 11;3(5875):323-5. doi: 10.1136/bmj.3.5875.323.
Smooth muscle antibodies (S.M.A.) were found in the sera of 81% of 126 patients over 10 years old with seropositive infectious mononucleosis tested within one month of onset. In 27 patients presenting clinically with infectious mononucleosis but having negative Paul-Bunnell tests the incidence of S.M.A. was 44%. In children 10 years of age or less in these two categories S.M.A. were present in 75% and 25% respectively, while in children of similar age not suspected of having infectious mononucleosis the incidence of S.M.A. was 10%. Among 45 adults with past histories of seropositive infectious mononucleosis more than one year before the incidence of S.M.A. was 33%, in contrast to 14% in 98 subjects with a negative history for infectious mononucleosis.
在发病后1个月内接受检测的126例10岁以上血清阳性传染性单核细胞增多症患者中，81%的患者血清中发现平滑肌抗体（S.M.A.）。在27例临床上表现为传染性单核细胞增多症但保罗-邦内尔试验呈阴性的患者中，S.M.A.的发生率为44%。在这两类10岁及以下的儿童中，S.M.A.的出现率分别为75%和25%，而在未怀疑患有传染性单核细胞增多症的同龄儿童中，S.M.A.的发生率为10%。在45例有血清阳性传染性单核细胞增多症病史且发病时间超过1年的成年人中，S.M.A.的发生率为33%，相比之下，在98例无传染性单核细胞增多症病史的受试者中，这一比例为14%。
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