Memon Muhammad Asif, Sandila Muhammad Perwaiz, Ahmed Syed Tausif
Department of Physiology, Ziauddin Medical University, Karachi.
J Pak Med Assoc. 2007 Apr;57(4):193-5.
To estimate the lung function prediction equation and to calculate appropriate normal reference values for the Pakistani adults living in Karachi.
Predicted equations for normal lung functions were derived from 504 healthy non-smoking subjects including 321 males and 183 females aged 15-65 years. The subjects underwent measurement of spirometric flow and volume. The following variables were measured: forced vital capacity (FVC), forced expiratory volume in one second (FEV1), maximal mid expiratory flow (MMEF) and peak expiratory flow (PEF). Regression analysis using height and age as independent variables were applied to provide predicted values for both sexes.
There was negative correlation between each pulmonary function and age. All parameters correlate positively with height. The largest negative correlation was found for FEV1 and FVC in males, while the largest positive correlation was observed for FVC in females.
In this study set of PFT reference values and prediction equations for both sexes have been derived using healthy, non-smoking urban Pakistani population which was different from several other prediction equations.
估算肺功能预测方程，并为居住在卡拉奇的巴基斯坦成年人计算合适的正常参考值。
从504名健康非吸烟受试者（包括321名男性和183名年龄在15 - 65岁的女性）中得出正常肺功能的预测方程。受试者接受了肺活量计流量和容积测量。测量了以下变量：用力肺活量（FVC）、一秒用力呼气容积（FEV1）、最大呼气中期流量（MMEF）和呼气峰值流量（PEF）。以身高和年龄作为自变量进行回归分析，以提供男女两性的预测值。
各肺功能与年龄之间呈负相关。所有参数均与身高呈正相关。男性中FEV1和FVC的负相关性最大，而女性中FVC的正相关性最大。
在本研究中，使用健康、不吸烟的巴基斯坦城市人群得出了男女两性的肺功能测试参考值和预测方程，这与其他几个预测方程不同。
