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对卡哈尔和高尔基在神经科学基础方面贡献的历史反思。

A historical reflection of the contributions of Cajal and Golgi to the foundations of neuroscience.

作者信息

De Carlos Juan A, Borrell José

机构信息

Instituto Cajal (CSIC), Avenida del Dr. Arce no. 37, E-28002-Madrid, Spain.

出版信息

Brain Res Rev. 2007 Aug;55(1):8-16. doi: 10.1016/j.brainresrev.2007.03.010. Epub 2007 Apr 5.

Abstract

In 1906, the Spaniard Santiago Ramón y Cajal and the Italian Camillo Golgi shared the Nobel Prize in Physiology or Medicine, in recognition of their work on the structure of the nervous system. Although both were well-known scientists who had made a large number of important discoveries regarding the anatomy of the nervous system, each defended a different and conflicting position in relation to the intimate organization of the grey matter that makes up the brain. In this communication we will review the importance of Cajal's studies using the method of impregnation discovered by Golgi, as well as the relevant studies carried out by Golgi, the concession of the Nobel Prize and the events that occurred during the Nobel conferences. In summary, we will précis the important contribution of both scientists to the founding of modern Neuroscience.

摘要

1906年,西班牙人圣地亚哥·拉蒙·卡哈尔和意大利人卡米洛·高尔基共同获得诺贝尔生理学或医学奖,以表彰他们在神经系统结构方面的研究工作。尽管两人都是著名科学家,在神经系统解剖学方面有大量重要发现,但在构成大脑的灰质的精细组织结构方面,他们各自秉持着不同且相互冲突的观点。在本交流文章中,我们将回顾卡哈尔运用高尔基发现的浸染法所做研究的重要性,以及高尔基所开展的相关研究、诺贝尔奖的授予情况以及诺贝尔颁奖仪式期间发生的事件。总之,我们将简述两位科学家对现代神经科学创立所做出的重要贡献。

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