Stabile Anna Maria, Pistilli Alessandra, Mariangela Ruggirello, Rende Mario, Bartolini Desirée, Di Sante Gabriele
Department of Medicine and Surgery, Section of Human, Clinical and Forensic Anatomy, University of Perugia, 60132 Perugia, Italy.
Department of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.
Diagnostics (Basel). 2023 Sep 15;13(18):2963. doi: 10.3390/diagnostics13182963.
Anatomic studies have traditionally relied on macroscopic, microscopic, and histological techniques to investigate the structure of tissues and organs. Anatomic studies are essential in many fields, including medicine, biology, and veterinary science. Advances in technology, such as imaging techniques and molecular biology, continue to provide new insights into the anatomy of living organisms. Therefore, anatomy remains an active and important area in the scientific field. The consolidation in recent years of some omics technologies such as genomics, transcriptomics, proteomics, and metabolomics allows for a more complete and detailed understanding of the structure and function of cells, tissues, and organs. These have been joined more recently by "omics" such as radiomics, pathomics, and connectomics, supported by computer-assisted technologies such as neural networks, 3D bioprinting, and artificial intelligence. All these new tools, although some are still in the early stages of development, have the potential to strongly contribute to the macroscopic and microscopic characterization in medicine. For anatomists, it is time to hitch a ride and get on board omics technologies to sail to new frontiers and to explore novel scenarios in anatomy.
传统上,解剖学研究依赖宏观、微观和组织学技术来研究组织和器官的结构。解剖学研究在许多领域至关重要,包括医学、生物学和兽医学。成像技术和分子生物学等技术进步不断为生物体的解剖结构提供新的见解。因此,解剖学仍然是科学领域一个活跃且重要的领域。近年来,基因组学、转录组学、蛋白质组学和代谢组学等一些组学技术的整合,使得人们能够更全面、详细地了解细胞、组织和器官的结构与功能。最近,受神经网络、3D生物打印和人工智能等计算机辅助技术支持的放射组学、病理组学和连接组学等“组学”也加入其中。所有这些新工具,尽管有些仍处于开发初期,但都有潜力为医学中的宏观和微观特征描述做出重大贡献。对于解剖学家来说,是时候搭上组学技术的便车,驶向新的前沿领域,探索解剖学的新场景了。