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霍普金斯狼疮妊娠中心:管理中的十个关键问题。

The Hopkins Lupus Pregnancy Center: ten key issues in management.

作者信息

Petri Michelle

机构信息

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

出版信息

Rheum Dis Clin North Am. 2007 May;33(2):227-35, v. doi: 10.1016/j.rdc.2007.01.003.

DOI:10.1016/j.rdc.2007.01.003
PMID:17499704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2704387/
Abstract

There is no consensus on the management of systemic lupus erythematosus (SLE), much less pregnancy in SLE patients. However, several key issues in the management of SLE in pregnancy are commonly faced by rheumatologists, nephrologists, and obstetricians. These include the treatment of SLE activity in pregnancy, the ascertainment of lupus nephritis, treatment of antiphospholipid antibodies, treatment of hypertension, and laboratory monitoring. These key issues will be examined in this chapter.

摘要

对于系统性红斑狼疮(SLE)的治疗尚无共识,更不用说SLE患者的妊娠管理了。然而,风湿病学家、肾病学家和产科医生在SLE妊娠管理中通常会面临几个关键问题。这些问题包括妊娠期SLE活动的治疗、狼疮性肾炎的诊断、抗磷脂抗体的治疗、高血压的治疗以及实验室监测。本章将探讨这些关键问题。

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本文引用的文献

1
Hydroxychloroquine in lupus pregnancy.狼疮妊娠中的羟氯喹
Arthritis Rheum. 2006 Nov;54(11):3640-7. doi: 10.1002/art.22159.
2
Risk of congenital anomalies in pregnant users of non-steroidal anti-inflammatory drugs: A nested case-control study.非甾体抗炎药孕期使用者的先天性异常风险:一项巢式病例对照研究。
Birth Defects Res B Dev Reprod Toxicol. 2006 Aug;77(4):268-79. doi: 10.1002/bdrb.20085.
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Major congenital malformations after first-trimester exposure to ACE inhibitors.孕早期接触血管紧张素转换酶抑制剂后出现的严重先天性畸形。
N Engl J Med. 2006 Jun 8;354(23):2443-51. doi: 10.1056/NEJMoa055202.
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Anti-inflammatory and immunosuppressive drugs and reproduction.抗炎和免疫抑制药物与生殖
Arthritis Res Ther. 2006;8(3):209. doi: 10.1186/ar1957. Epub 2006 May 11.
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Cyclophosphamide for lupus during pregnancy.孕期狼疮使用环磷酰胺。
Lupus. 2005;14(8):593-7. doi: 10.1191/0961203305lu2169oa.
6
The impact of increased lupus activity on obstetric outcomes.狼疮活动增加对产科结局的影响。
Arthritis Rheum. 2005 Feb;52(2):514-21. doi: 10.1002/art.20864.
7
Pregnancy, cytokines, and disease activity in systemic lupus erythematosus.妊娠、细胞因子与系统性红斑狼疮的疾病活动度
Arthritis Rheum. 2004 Dec 15;51(6):989-95. doi: 10.1002/art.20837.
8
Mycophenolate mofetil in pregnancy after renal transplantation: a case of major fetal malformations.肾移植后妊娠使用霉酚酸酯:一例严重胎儿畸形病例
Obstet Gynecol. 2004 May;103(5 Pt 2):1091-4. doi: 10.1097/01.AOG.0000124986.32858.ba.
9
Outcomes at school age after postnatal dexamethasone therapy for lung disease of prematurity.早产肺疾病产后地塞米松治疗后的学龄期结局
N Engl J Med. 2004 Mar 25;350(13):1304-13. doi: 10.1056/NEJMoa032089.
10
Cigarette smoking and the risk of systemic lupus erythematosus: a meta-analysis.吸烟与系统性红斑狼疮风险:一项荟萃分析。
Arthritis Rheum. 2004 Mar;50(3):849-57. doi: 10.1002/art.20049.