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留置输尿管支架与性健康:一项前瞻性多变量分析。

Indwelling ureteral stents and sexual health: a prospective, multivariate analysis.

作者信息

Sighinolfi M C, Micali S, De Stefani S, Mofferdin A, Grande M, Giacometti M, Ferrari N, Rivalta M, Bianchi G

机构信息

Department of Urology, University of Modena, Italy.

出版信息

J Urol. 2007 Jul;178(1):229-31. doi: 10.1016/j.juro.2007.03.039. Epub 2007 May 17.

DOI:10.1016/j.juro.2007.03.039
PMID:17499774
Abstract

PURPOSE

Ureteral stents are common devices in urological practice. However, a stent may provoke lower urinary tract symptoms that severely affect quality of life. We evaluated the relationship between ureteral stents and male erection/female sexuality.

MATERIALS AND METHODS

A total of 30 men and 20 women undergoing ureteral stent positioning were considered. Patients affected by risk factors for erectile dysfunction or hormonal and metabolic alterations were excluded. Hystero-ovariectomy and menopause were considered exclusion criteria. Three questionnaires were administered before stenting and 45 to 60 days after stent positioning, including the International Prostate Symptom Score, the International Index of Erectile Function-5 for men and the Female Sexual Function Index for women.

RESULTS

Mean age was 45 years in men and 39 years in women. The mean+/-SD International Index of Erectile Function-5 score was 23.2+/-1.27 and the mean Female Sexual Function Index score was 32.15+/-2.71 before stent positioning. No lower urinary tract symptoms were reported before the procedure. After the ureteral stent was indwelling the mean International Index of Erectile Function-5 score was 13.5+/-4.01 and the mean Female Sexual Function Index score was 23.6+/-14.66 (p=0.000 and 0.007, respectively). Of 30 men 25 reported a pathological International Index of Erectile Function-5 score and 6 of 20 women denied any sexual activity due to stent related anxiety, resulting in the minimum Female Sexual Function Index score. In the remaining 14 women sexual life was not significantly impaired by the ureteral stent (p=0.08).

CONCLUSIONS

Ureteral stents impaired the quality of sexual life in male and female subjects. In men the most important distress was in regard to erectile function, probably related to lower urinary tract symptoms. Conversely female sexuality appeared to be severely impaired due to stent related psychological concerns.

摘要

目的

输尿管支架是泌尿外科常见的器械。然而,支架可能引发下尿路症状,严重影响生活质量。我们评估了输尿管支架与男性勃起/女性性功能之间的关系。

材料与方法

共纳入30名接受输尿管支架置入的男性和20名接受输尿管支架置入的女性。排除患有勃起功能障碍风险因素或激素及代谢改变的患者。子宫卵巢切除术和绝经被视为排除标准。在支架置入前以及支架置入后45至60天发放三份问卷,包括国际前列腺症状评分、男性国际勃起功能指数-5以及女性性功能指数。

结果

男性平均年龄为45岁,女性平均年龄为39岁。支架置入前,国际勃起功能指数-5评分的平均值±标准差为23.2±1.27,女性性功能指数评分的平均值为32.15±2.71。术前未报告下尿路症状。输尿管支架留置后,国际勃起功能指数-5评分的平均值为13.5±4.01,女性性功能指数评分的平均值为23.6±14.66(分别为p = 0.000和0.007)。30名男性中有25名报告国际勃起功能指数-5评分病理性升高,20名女性中有6名因与支架相关的焦虑而否认有任何性活动,导致女性性功能指数评分最低。其余14名女性的性生活未因输尿管支架而受到显著损害(p = 0.08)。

结论

输尿管支架损害了男性和女性的性生活质量。对男性而言,最重要的困扰在于勃起功能,可能与下尿路症状有关。相反,女性性功能似乎因与支架相关的心理问题而受到严重损害。

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Re: Indwelling ureteral stents and sexual health: a prospective, multivariate analysis. M. C. Sighinolfi, S. Micali, S. De Stefani, A. Mofferdin, M. Grande, M. Giacometti, N. Ferrari, M. Rivalta and G. Bianchi. J Urol 2007; 178: 229-231.
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