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马拉色菌属的最新研究进展。

Update on the genus Malassezia.

作者信息

Ashbee H R

机构信息

Mycology Reference Centre, Department of Microbiology, Leeds General Infirmary, Leeds, UK.

出版信息

Med Mycol. 2007 Jun;45(4):287-303. doi: 10.1080/13693780701191373.

DOI:10.1080/13693780701191373
PMID:17510854
Abstract

Malassezia yeasts are commensals of normal human skin, but also cause pityriasis versicolor, seborrhoeic dermatitis and evidence is accumulating that they play a significant role in atopic eczema/dermatitis syndrome (AEDS; formerly atopic dermatitis). The taxonomy of the genus has changed considerably and is likely to change more in the future. Our understanding of the interaction between Malassezia and the host demonstrates that it has the paradoxical ability to both stimulate and suppress the immune response directed against it and there is a fine balance in its existence at the interface between commensalism and pathogenicity.

摘要

马拉色菌酵母是人类正常皮肤的共生菌,但也会引起花斑癣、脂溢性皮炎,并且越来越多的证据表明它们在特应性湿疹/皮炎综合征(AEDS;原称特应性皮炎)中起重要作用。该属的分类已经发生了很大变化,未来可能还会有更多变化。我们对马拉色菌与宿主之间相互作用的理解表明,它具有既刺激又抑制针对它的免疫反应的矛盾能力,并且在共生与致病的界面上其生存存在着微妙的平衡。

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