Luo Zhuodi, Li Xiaowei, Zhou Zhen, Shi Jing, Chen Hulin, Wang Yunan, Xu Linli, Liang Huazhuo
Department of Dermatology and Venereology, Guangdong Women and Children Hospital, Guangzhou, 511442, China.
Department of Dermatology and Venereology, Women and Children's Hospital, Southern University of Science and Technology, Guangzhou, 511442, China.
Arch Dermatol Res. 2025 May 21;317(1):776. doi: 10.1007/s00403-025-04276-x.
Pityriasis versicolor (PV) is a common chronic superficial fungal infection caused by the lipophilic yeast Malassezia, which is highly prevalent in young and middle-aged people, and its incidence in children, especially infants, has been poorly studied. The aim was to study the epidemiology, clinical features and mycological correlates of PV in children. A total of 415 patients under 14 years of age with a clinical diagnosis of PV who presented to the Department of Dermatology between 1 January 2023 and 31 December 2024 were included. Skin scrapings from these patients were examined by fluorescence microscopy. Of the 415 patients with PV, 71.57% were male and 28.43% were female; the age group with the highest percentage of patients was the group aged less than 6 months (35.42%); the youngest patient affected was a 1-month, 15-day-old boy, and the oldest was a 14-year-old male. The duration of infection ranged from 1 to 6 months in 46.75% of the children, and 4.10% of the patients had infections lasting longer than 1 year. The face was the most frequently involved site (65.29%), and hypopigmented PV was the most common clinical presentation, observed in 96.87% of the patients. A fluorescence microscope revealed that Malassezia was most commonly observed in hyphal and spore forms (38.80%), followed by spore forms alone (31.80%). The retrospective nature of the study. PV is common in children, especially in infants less than 6 months old, and the face is a frequently involved site in children with PV.
花斑糠疹（PV）是一种由亲脂性酵母马拉色菌引起的常见慢性浅表真菌感染，在中青年中高度流行，而其在儿童尤其是婴儿中的发病率研究较少。目的是研究儿童花斑糠疹的流行病学、临床特征及真菌学相关性。纳入了2023年1月1日至2024年12月31日期间到皮肤科就诊、临床诊断为花斑糠疹的415例14岁以下患者。对这些患者的皮肤刮屑进行荧光显微镜检查。在415例花斑糠疹患者中，男性占71.57%，女性占28.43%；患者比例最高的年龄组是小于6个月的组（35.42%）；受影响最小的患者是一名1个月15天大的男孩，最大的是一名14岁男性。46.75%的儿童感染持续时间为1至6个月，4.10%的患者感染持续时间超过1年。面部是最常受累部位（65.29%），色素减退型花斑糠疹是最常见的临床表现，在96.87%的患者中观察到。荧光显微镜显示，马拉色菌最常见的形态是菌丝和孢子形式（38.80%），其次是仅孢子形式（31.80%）。本研究具有回顾性。花斑糠疹在儿童中很常见，尤其是在6个月以下的婴儿中，面部是花斑糠疹患儿常受累的部位。
