Zloczower Moshe, Reznick Abraham Z, Zouby Rula Obeid, Nagler Rafael M
Endocrine Department and Diabetes in Pregnancy Clinic, Rambam Medical Center, Haifa, Israel.
Antioxid Redox Signal. 2007 Jun;9(6):765-73. doi: 10.1089/ars.2007.1515.
Can salivary free radicals and antioxidant parameters be useful in general diagnosis and evaluation of diabetes mellitus Type II (DM)? Serum and salivary redox state of 40 diabetes mellitus patients were examined and compared with 20 controls. The involvement of salivary gland in diabetes mellitus has been suggested based on salivary flow rate and compositional alterations. In addition, the redox state of saliva of diabetes mellitus patients is different than that of normoglycemic control human subjects. This observation unveils the opportunity to use noninvasive saliva-based diagnostics for diabetes mellitus patients.
唾液中的自由基和抗氧化参数能否用于2型糖尿病（DM）的一般诊断和评估？对40例糖尿病患者的血清和唾液氧化还原状态进行了检测，并与20名对照者进行了比较。基于唾液流速和成分改变，有人提出唾液腺参与了糖尿病的发病过程。此外，糖尿病患者唾液的氧化还原状态与血糖正常的对照人群不同。这一观察结果揭示了对糖尿病患者使用基于唾液的非侵入性诊断方法的可能性。
