Miaskowski Christine, Aouizerat Bradley E
Department of Physiological Nursing, University of California, San Francisco, CA 94143-0610, USA.
Semin Oncol Nurs. 2007 May;23(2):99-105. doi: 10.1016/j.soncn.2007.01.008.
To examine symptom clusters in oncology patients; to determine if these symptom clusters might share a common biologic mechanism; and to describe potential biologic mechanisms that warrant investigation.
Synthesis of the theoretical and research papers on symptom clusters.
Definitive conclusions about whether there is a biologic basis for the clustering of symptoms cannot be determined at this time. The animal model of sickness behavior holds promise as a potential biologic mechanism for clustering symptoms.
Until more definitive studies of symptom clusters are performed, clinicians need to monitor patients for the co-occurrence of multiple symptoms and develop appropriate management plans.
研究肿瘤患者的症状群；确定这些症状群是否可能共享一种共同的生物学机制；并描述值得研究的潜在生物学机制。
关于症状群的理论和研究论文的综合。
目前尚无法确定症状群是否存在生物学基础的确切结论。疾病行为的动物模型有望成为症状群的潜在生物学机制。
在对症状群进行更明确的研究之前，临床医生需要监测患者是否出现多种症状，并制定适当的管理计划。
