Lokko Phoebe, Lartey Anna, Armar-Klemesu Margaret, Mattes Richard D
Food Research Institute, Accra, Ghana.
Int J Food Sci Nutr. 2007 May;58(3):190-200. doi: 10.1080/09637480701198067.
To determine whether the daily intake of 2,092 kJ (500 kcal) from peanuts will improve the lipid profiles and diet quality of healthy Ghanaians.
A 30-week, randomized, cross-over trial study was conducted with healthy adults.
There were three treatment arms: Treatment 1 (T1), subjects were provided 2,092 kJ/day (500 kcal/day) peanuts to incorporate into their daily diet for 8 weeks at any time and in any form they chose; Treatment 2 (T2), subjects were provided 2,092 kJ/day (500 kcal/day) peanuts and were instructed to consume them in addition to their customary daily diet for 3 weeks; Treatment 3 (T3), substitution of 2,092 kJ/day fat, with energy from peanuts. Total cholesterol, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol and triglyceride were measured at baseline, week 4 and week 8 (T1 and T3) or at baseline and week 3 (T2). Three-day dietary intake records were kept during each treatment.
There was significant decrease in total cholesterol (7.2%) and triacylglycerol (20.0%) after T1. However, individually, high-density lipoprotein-cholesterol and low-density lipoprotein-cholesterol levels did not change significantly. Total fat intake increased by 9%, due to elevations of monounsaturated fatty acid of 60% and polyunsaturated fatty acid of 50%. Similar non-significant trends were observed during T2 and T3.
The results suggest that regular consumption of peanuts lowers the total cholesterol and triacylglycerol concentrations among healthy Ghanaians. Regular consumption of peanuts should therefore be encouraged.
确定每天从花生中摄入2092千焦（500千卡）的热量是否会改善健康加纳人的血脂状况和饮食质量。
对健康成年人进行了一项为期30周的随机交叉试验研究。
有三个治疗组：治疗1组（T1），为受试者提供2092千焦/天（500千卡/天）的花生，让他们在8周内以任何他们选择的时间和形式将其纳入日常饮食；治疗2组（T2），为受试者提供2092千焦/天（500千卡/天）的花生，并指示他们在日常习惯饮食之外食用3周；治疗3组（T3），用花生中的能量替代2092千焦/天的脂肪。在基线、第4周和第8周（T1和T3）或基线和第3周（T2）测量总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和甘油三酯。在每次治疗期间记录三天的饮食摄入量。
T1后总胆固醇（7.2%）和三酰甘油（20.0%）显著降低。然而，高密度脂蛋白胆固醇和低密度脂蛋白胆固醇水平个体上没有显著变化。由于单不饱和脂肪酸升高60%和多不饱和脂肪酸升高50%，总脂肪摄入量增加了9%。在T2和T3期间观察到类似的不显著趋势。
结果表明，经常食用花生可降低健康加纳人的总胆固醇和三酰甘油浓度。因此，应鼓励经常食用花生。
