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遗传和环境因素对青少年同伴饮酒与自身饮酒之间关系的影响。

Genetic and environmental influences on the relationship between peer alcohol use and own alcohol use in adolescents.

作者信息

Fowler Tom, Shelton Katherine, Lifford Kate, Rice Frances, McBride Andrew, Nikolov Ivan, Neale Michael C, Harold Gordon, Thapar Anita, van den Bree Marianne B M

机构信息

Department of Psychological Medicine, Cardiff University, Cardiff, UK.

出版信息

Addiction. 2007 Jun;102(6):894-903. doi: 10.1111/j.1360-0443.2007.01824.x.

DOI:10.1111/j.1360-0443.2007.01824.x
PMID:17523983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1974773/
Abstract

AIMS

Genetically influenced aspects of adolescent behaviour can play a role in alcohol use and peer affiliation. We explored the correlations between friends' alcohol use and adolescent own use with a genetically sensitive design.

DESIGN

Genetic and environmental factors were estimated on adolescent reports of their friends' alcohol use and their own use and problem use of alcohol. The correlations between the genetic and environmental factors that influence friends' alcohol use and adolescent own alcohol use and problem use were also estimated.

PARTICIPANTS

A total of 862 twin pairs aged 11-17 years sampled from the UK population-based Cardiff Study of All Wales and North-west of England Twins (CaStANET).

MEASUREMENTS

Data on adolescent own alcohol use and problem use and the alcohol use of their three best friends were obtained using self-report questionnaires.

FINDINGS

A significant genetic influence was found on adolescent friends' alcohol use (about 30%). Significant correlations of 0.60 and 0.70 were found between the genetic influences on friends' alcohol use and adolescents' own use and problem use of alcohol. Common environmental influences were almost completely correlated for friends' alcohol use and adolescents' own alcohol use and problem use (0.91 and 0.94).

CONCLUSIONS

There is considerable overlap in the common environmental and genetic factors that contribute to the relationship between adolescents' own alcohol use and that of their friends. These findings contribute to understanding of the mechanisms by which friends' alcohol use influences adolescent drinking behaviour.

摘要

目的

青少年行为中受遗传影响的方面可能在饮酒和同伴关系中起作用。我们采用基因敏感性设计探讨了朋友饮酒与青少年自身饮酒之间的相关性。

设计

根据青少年对其朋友饮酒情况以及自身饮酒和饮酒问题的报告，对遗传和环境因素进行评估。还估计了影响朋友饮酒、青少年自身饮酒及饮酒问题的遗传和环境因素之间的相关性。

参与者

从基于英国人口的威尔士和英格兰西北部双胞胎卡迪夫研究（CaStANET）中抽取了862对年龄在11至17岁的双胞胎。

测量

通过自我报告问卷获得青少年自身饮酒及饮酒问题以及他们三个最好朋友饮酒情况的数据。

研究结果

发现遗传因素对青少年朋友的饮酒有显著影响（约30%）。在朋友饮酒的遗传影响与青少年自身饮酒及饮酒问题之间发现了显著相关性，分别为0.60和0.70。朋友饮酒、青少年自身饮酒及饮酒问题的共同环境影响几乎完全相关（0.91和0.94）。

结论

导致青少年自身饮酒与其朋友饮酒之间关系的共同环境和遗传因素存在相当大的重叠。这些发现有助于理解朋友饮酒影响青少年饮酒行为的机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d2e/1974773/435fe1a4e7c4/add0102-0894-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d2e/1974773/435fe1a4e7c4/add0102-0894-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d2e/1974773/435fe1a4e7c4/add0102-0894-f1.jpg

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