Hayes Don
Department of Pediatrics, University of Kentucky College of Medicine, Lexington, Kentucky 40536, USA.
J Asthma. 2007 May;44(4):253-5. doi: 10.1080/02770900701246782.
Tracheopathia osteoplastica (TPO) is a rare disorder characterized by cartilaginous or bony mucosal nodules in the tracheobronchial tree. Due to most patients being asymptomatic, the majority are diagnosed post-mortem. If symptoms are present, they typically include chronic cough, dyspnea, hemoptysis, hoarseness, and wheezing, with some of these symptoms overlapping with asthma. This case report describes an adult female with chronic cough who was diagnosed with asthma that was refractory to therapy for 8 years. Computed tomography (CT) of the chest revealed several soft tissue masses in the trachea with bronchoscopy revealing TPO in the upper portion of the trachea. She was diagnosed with TPO and started on airway clearance and a nasal corticosteroid spray with resolution of the cough at follow-up 3 months later.
气管骨化症（TPO）是一种罕见的疾病，其特征是气管支气管树中出现软骨或骨性黏膜结节。由于大多数患者无症状，多数病例是在尸检时被诊断出来的。如果出现症状，通常包括慢性咳嗽、呼吸困难、咯血、声音嘶哑和喘息，其中一些症状与哮喘重叠。本病例报告描述了一名成年女性，她患有慢性咳嗽，被诊断为哮喘，且对治疗耐药8年。胸部计算机断层扫描（CT）显示气管内有几个软组织肿块，支气管镜检查显示气管上部存在气管骨化症。她被诊断为气管骨化症，并开始进行气道清理和使用鼻用皮质类固醇喷雾剂，3个月后的随访显示咳嗽症状消失。
