Verhoeven E W M, Kraaimaat F W, van de Kerkhof P C M, van Weel C, Duller P, van der Valk P G M, van den Hoogen H J M, Bor J H J, Schers H J, Evers A W M
Department of Medical Psychology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Br J Dermatol. 2007 Jun;156(6):1346-9. doi: 10.1111/j.1365-2133.2007.07916.x.
Physical symptoms of skin diseases have been shown to negatively affect patients' wellbeing. Although insight into physical symptoms accompanying skin diseases is relevant for the management and treatment of skin diseases, the prevalence of physical symptoms among patients with skin diseases is a rather unexplored territory.
The goal of the present study was to examine the prevalence of physical symptoms of itch, pain and fatigue in patients with skin diseases.
On the basis of a systematic morbidity registration system in primary care, questionnaires were sent to 826 patients with skin diseases. Eventually, questionnaires from 492 patients were suitable for our analyses.
Results indicated that patients with skin diseases particularly experience symptoms of itch and fatigue. Approximately 50% of all patients report experiencing these symptoms and about 25% experience these symptoms as relatively severe. Pain was relatively less frequently reported by 23% of all patients, and was on average somewhat less intense. The physical symptoms showed relatively strong correlations with disease-related quality of life and self-reported disease severity. In contrast, only moderate correlations were found with comorbidity and demographic variables, which suggests that the physical symptoms of itch, pain and fatigue are consequences of the skin diseases.
Itch and fatigue and, to a somewhat lesser extent, pain have a high prevalence among patients with skin diseases. Clinicians should be encouraged to carefully assess itch, pain and fatigue in patients with skin diseases, and where appropriate focus treatment to these symptoms.
皮肤病的身体症状已被证明会对患者的健康产生负面影响。尽管了解皮肤病伴随的身体症状对于皮肤病的管理和治疗至关重要,但皮肤病患者中身体症状的患病率仍是一个尚未充分探索的领域。
本研究的目的是调查皮肤病患者中瘙痒、疼痛和疲劳等身体症状的患病率。
基于基层医疗中的一个系统发病登记系统,向826名皮肤病患者发送了问卷。最终,492名患者的问卷适合我们的分析。
结果表明,皮肤病患者特别容易出现瘙痒和疲劳症状。所有患者中约50%报告有这些症状,约25%的患者认为这些症状较为严重。23%的所有患者相对较少报告疼痛,且疼痛程度平均略轻。身体症状与疾病相关生活质量和自我报告的疾病严重程度显示出较强的相关性。相比之下,与合并症和人口统计学变量仅发现中度相关性,这表明瘙痒、疼痛和疲劳等身体症状是皮肤病的后果。
瘙痒和疲劳,以及在较小程度上的疼痛,在皮肤病患者中患病率很高。应鼓励临床医生仔细评估皮肤病患者的瘙痒、疼痛和疲劳情况,并在适当情况下针对这些症状进行治疗。