通过形态学和基于序列的方法鉴定为蒜臭曲霉（无性型为蒜臭曲霉）的非产孢临床分离株。
Nonsporulating clinical isolate identified as Petromyces alliaceus (anamorph Aspergillus alliaceus) by morphological and sequence-based methods.
作者信息
Balajee S Arunmozhi, Lindsley Mark D, Iqbal Naureen, Ito James, Pappas Peter G, Brandt Mary E
机构信息
Mycotic Diseases Branch, Centers for Disease Control and Prevention, Mail Stop-G 11, 1600 Clifton Road, Atlanta, GA 30333, USA.
出版信息
J Clin Microbiol. 2007 Aug;45(8):2701-3. doi: 10.1128/JCM.00642-07. Epub 2007 May 30.
Abstract
Concerted morphological and sequencing-based strategies revealed the identity of a nonsporulating clinical isolate as Petromyces alliaceus (anamorph Aspergillus alliaceus). This rare Aspergillus sp. was recovered as the etiological agent of invasive pulmonary aspergillosis and had reduced in vitro susceptibilities to amphotericin B and caspofungin, which correlated with clinical failure of therapy.
摘要
基于形态学和测序的协同策略揭示了一株非产孢临床分离株为蒜臭曲霉（无性型为蒜臭曲霉）。这种罕见的曲霉菌种作为侵袭性肺曲霉病的病原体被分离出来，并且对两性霉素B和卡泊芬净的体外敏感性降低，这与治疗的临床失败相关。
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