Bertrand A, Jourdan J, Prefaut Ch
Sem Hop. 1975 Feb 26;51(10):667-76.
Among the various infectious and parasitic disease liable to produce granulopenia, the authors selected certain diseases which represented their personal experience. Classically, leukopenia may occur during typhoid fever, but was not present in all of the series of 114 adults they observed with this disease. It only occurs after antibiotic treatment (Thiamphenicol in the majority of cases). During acute brucellosis (188 cases studied) granulopenia was constant. It occurs early and is lasting. It reappears during septicemic relapse. Leukopenia is corrected during treatment by tetracycline antibiotics. Neutropenia during disease is frequent but usually labile. This characteristic explains why there was no granulopenia in 90 cases of mumps and 64 cases of chickenpox. Finally, during Kala Azar, 8 cases confirmed certain already well known data: the considerable reduction in granulocytes but also anemia and thrombocytopenia.
在各种易导致粒细胞减少症的感染性和寄生虫病中，作者挑选了一些代表其个人经验的疾病。传统上，伤寒热期间可能会出现白细胞减少症，但在他们观察的114例成年伤寒患者中并非全部出现。它仅在抗生素治疗后出现（大多数情况下是甲砜霉素）。在急性布鲁氏菌病（研究了188例）中，粒细胞减少症持续存在。它出现得早且持续时间长。在败血症复发期间会再次出现。治疗期间用四环素类抗生素可纠正白细胞减少症。患病期间中性粒细胞减少症很常见，但通常不稳定。这一特征解释了为什么90例腮腺炎和64例水痘患者中没有出现粒细胞减少症。最后，在黑热病中，8例病例证实了某些已为人熟知的数据：粒细胞显著减少，同时伴有贫血和血小板减少症。
