Desai Bharat M
St. Anthony's Central Hospital, Panorama Orthopedic Clinic and Spine Center, Denver, Colorado, USA.
Am J Orthop (Belle Mead NJ). 2007 Apr;36(4 Suppl):8-11.
Osteobiologic adjuvants that aid in bone grafting have recently been popularized. Current osteobiologic technologies can be organized into 3 main categories: osteoconductive, osteogenic, and osteoinductive. Appropriate use of osteobiologic agents mimics autograft. Compared with autograft , synthetic adjuvants minimize donor morbidity. Understanding how synthetic agents can enhance bone formation and their appropriate use can aid the orthopedic surgeon in delivering optimal care in these difficult cases. The understanding of how synthetic grafts can enhance the normal bone healing cascade defines their role and use in treating fracture gaps.
有助于骨移植的骨生物佐剂最近已得到推广。当前的骨生物技术可分为三大类：骨传导性、骨生成性和成骨诱导性。合理使用骨生物制剂可模拟自体骨移植。与自体骨移植相比，合成佐剂可将供体发病率降至最低。了解合成制剂如何促进骨形成及其合理使用，有助于骨科医生在这些复杂病例中提供最佳治疗。了解合成移植物如何增强正常的骨愈合过程，可明确其在治疗骨折间隙中的作用和用途。
