Sollom A C, Kneebone I I
Haslemere Hospital, Surrey NHS Primary Care Trust, Haslemere, and Department of Psychology, University of Surrey, Guilford, UK.
Mult Scler. 2007 Jun;13(5):632-5. doi: 10.1177/1352458507072384. Epub 2007 Feb 9.
Depression is common among people with multiple sclerosis (MS). Research suggests that treatments for depression are effective in this population, though few patients appear to access these treatments. Our objectives were to consider whether persons with MS and significant depressive symptoms, prompted to seek treatment by letter, did so, what professionals they consulted, and the benefits of any treatment obtained. A total of 495 individuals with MS (401 female; 94 male), aged 22-65 years (mean: 45.8 years), were surveyed in three phases at yearly intervals. Significant depressive symptoms were found over the three phases (50-60.2%). Despite a high prevalence of depressive symptoms, few participants sought treatment, even though prompted to do so. Where treatment was sought, general practitioners remained the principal group consulted. Contrary to previous reports of the efficacy of treatment in clinical trials, no strong support for this was found. Future research needs to consider why the majority of people with MS do not seek treatment for depression, and why interventions, which are not clinical trials, seem to lack effectiveness.
抑郁症在多发性硬化症（MS）患者中很常见。研究表明，抑郁症的治疗方法对这一人群有效，尽管似乎很少有患者能接受这些治疗。我们的目标是探讨患有MS且有明显抑郁症状的人在收到信件提示后是否会寻求治疗，他们咨询了哪些专业人士，以及所接受的任何治疗的效果。共有495名MS患者（401名女性；94名男性），年龄在22至65岁之间（平均45.8岁），每年进行三个阶段的调查。在这三个阶段中均发现有明显的抑郁症状（50 - 60.2%）。尽管抑郁症状的患病率很高，但很少有参与者寻求治疗，即使收到了提示。在寻求治疗的人群中，全科医生仍是主要咨询对象。与之前关于临床试验中治疗效果的报告相反，未发现对此的有力支持。未来的研究需要考虑为什么大多数MS患者不寻求抑郁症治疗，以及为什么非临床试验的干预措施似乎缺乏效果。
