来自人类免疫缺陷病毒患者口咽部位以及巴伐利亚州环境中的酿酒葡萄的酵母对医学和农业用唑类药物的交叉耐药性。
Cross-resistance to medical and agricultural azole drugs in yeasts from the oropharynx of human immunodeficiency virus patients and from environmental Bavarian vine grapes.
作者信息
Müller Frank-Michael C, Staudigel Andrea, Salvenmoser Stefanie, Tredup Antje, Miltenberger Rudolf, Herrmann Josef V
机构信息
Pediatric Pulmonology and Infectious Diseases, Dept of Pediatrics III, University Heidelberg, Im Neuenheimer Feld 153, Heidelberg, Germany.
出版信息
Antimicrob Agents Chemother. 2007 Aug;51(8):3014-6. doi: 10.1128/AAC.00459-07. Epub 2007 Jun 4.
Abstract
Cross-resistance among Candida albicans isolates from the oropharynges of human immunodeficiency virus-infected patients (n = 16) and environmental yeast strains of various species (n = 54) to medical and agricultural azole drugs was observed. Precautions against the unnecessary widespread use of azoles in the environment and human medicine are strongly recommended to prevent patients from acquiring azole-resistant yeasts.
摘要
观察到从人类免疫缺陷病毒感染患者的口咽部分离出的白色念珠菌菌株（n = 16）和各种环境酵母菌株（n = 54）对医学和农业用唑类药物存在交叉耐药性。强烈建议采取预防措施，避免在环境和人类医学中不必要地广泛使用唑类药物，以防止患者感染唑类耐药酵母。
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