Habeeb Fatema, Stables Graham, Bradbury Fiona, Nong Stephanie, Cameron Pamela, Plevin Robin, Ferro Valerie A
Faculty of Allied Health, Medical Laboratory Sciences, Kuwait University, P.O. Box 31470, Sulaibikhat 90805, Kuwait.
Methods. 2007 Aug;42(4):388-93. doi: 10.1016/j.ymeth.2007.03.005.
The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-alpha and IL-1 beta, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.
本研究旨在检测库拉索芦荟叶内凝胶成分的抗炎活性。设计了一种简单的体外试验，以确定内凝胶对弗氏志贺菌或脂多糖刺激的外周血白细胞产生的细菌诱导促炎细胞因子（即肿瘤坏死因子-α和白细胞介素-1β）的影响。本报告描述了用冻干内凝胶粉末和来自同一来源的商业健康饮料对这两种细胞因子的抑制作用。与人类单核细胞系（THP-1细胞）进行了比较，并证明了类似的反应趋势。
