Theorell Töres, Liljeholm-Johansson Yvonne, Björk Helena, Ericson Mats
National Institute for Psychosocial Medicine, P.O. Box 230, 17177 Stockholm, Sweden.
Psychoneuroendocrinology. 2007 Jul;32(6):660-8. doi: 10.1016/j.psyneuen.2007.04.006. Epub 2007 Jun 8.
Musicians are sensitive to changes in their work environment. A 2-year longitudinal study with repeated observations was performed in two professional symphony orchestras. A representative sample from each one of them was selected, 15 and 16 members respectively. In one of them a wind player fainted twice in front of the audience shortly preceding and coinciding with the start of the study. Changes in two indicators that reflect regenerative/anabolic and parasympathetic tone, saliva testosterone concentration (STC) and very low-frequency power (VLFP) in heart rate variability were followed in relation to this dramatic change. Saliva samples and 24-h ECG heart rate variability recordings were collected on five occasions every 6 months during a 2-year period. No changes were seen in the control orchestra whereas the levels showed a pronounced rise in the intervention orchestra during the first part of the study, starting from low levels. VLFP showed a similar pattern, with initially low and then rising level in the intervention orchestra and higher stable level in the other group. In the total study group, a rise in STC over the whole observation period was significantly correlated with increase in VLFP and also significantly correlated with a decrease in low/high-frequency power ratio in heart rate variability. The changes observed in the anabolic/regenerative STC and the parasympathetically influenced VLFP may reflect changes in the work environment associated with the faintings.
音乐家对其工作环境的变化很敏感。在两个专业交响乐团中进行了一项为期两年的纵向研究，并进行了多次观察。从每个乐团中分别选取了一个具有代表性的样本，分别为15名和16名成员。其中一个乐团里，一名管乐演奏者在研究开始前不久且恰逢研究开始时，在观众面前晕倒了两次。针对这一戏剧性变化，跟踪了反映再生/合成代谢和副交感神经张力的两个指标的变化，即唾液睾酮浓度（STC）和心率变异性中的极低频功率（VLFP）。在两年期间，每6个月收集5次唾液样本和24小时心电图心率变异性记录。对照组乐团未出现变化，而干预组乐团在研究的第一阶段，从低水平开始，各项指标呈现出明显上升。VLFP呈现出类似的模式，干预组乐团最初较低，随后上升，而另一组则保持较高的稳定水平。在整个研究组中，整个观察期内STC的升高与VLFP的增加显著相关，也与心率变异性中低/高频功率比的降低显著相关。在合成代谢/再生的STC和受副交感神经影响的VLFP中观察到的变化，可能反映了与晕倒事件相关的工作环境变化。
