Wenzel Richard P, Bearman Gonzalo, Edmond Michael B
Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, and Medical College of Virginia Hospitals, 1101 East Broad Street, P.O. Box 980663, Richmond, VA 23298, USA.
Int J Antimicrob Agents. 2007 Sep;30(3):210-2. doi: 10.1016/j.ijantimicag.2007.04.003. Epub 2007 Jun 12.
The emergence and clonal expansion of strains of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) have created new challenges with their entrance to hospitals. The increased virulence of CA-MRSA in concert with the depressed immunity of inpatients may cause added morbidity and mortality expected from healthcare-associated infections. Questions about changing prophylactic and empirical therapy as well as the use of intravenous immunoglobulin for life-threatening infections are addressed.
社区获得性耐甲氧西林金黄色葡萄球菌（CA-MRSA）菌株的出现和克隆性扩张，随着它们进入医院带来了新的挑战。CA-MRSA毒力的增加，再加上住院患者免疫力的下降，可能会导致医疗相关感染预期的发病率和死亡率上升。文中探讨了关于改变预防性和经验性治疗以及使用静脉注射免疫球蛋白治疗危及生命感染的问题。
