Braune H J
Neurologische Universitätsklinik, Pilipps-Universität Marburg/Lahn.
Fortschr Neurol Psychiatr. 1991 Nov;59(11):456-67. doi: 10.1055/s-2007-1000721.
The tick-borne Lyme Borreliosis may lead to a wide variety of sequels. Besides symptoms involving skin, joints and heart the infection provokes as a neurologic complication a meningopolyneuritis Garin-Bujadoux-Bannwarth in second state and a progressive encephalomyelitis in third state. Unexpected widespread--as modern laboratory investigations proved--the contamination only occasionally inflicts clinical manifestations. Involvement of the nervous system is substantiated by the demonstration of endogenous Borrelia antibodies in the cerebrospinal fluid. This prove is to claim especially for the assumption of a third state neuroborreliosis with progressive encephalomyelitis. Severe damage can be prevented by prompt diagnosis, specific treatment and follow-up.
蜱传莱姆病可能会导致各种各样的后遗症。除了涉及皮肤、关节和心脏的症状外,该感染在第二阶段会引发一种神经并发症——加林-布雅杜-班沃思脑膜多神经炎,在第三阶段会引发进行性脑脊髓炎。正如现代实验室研究所证明的,这种感染出人意料地广泛传播,但仅偶尔会引发临床表现。脑脊液中内源性伯氏疏螺旋体抗体的检测证实了神经系统受到了感染。这一证据尤其支持了存在第三阶段伴有进行性脑脊髓炎的神经莱姆病的假设。通过及时诊断、特异性治疗和随访,可以预防严重损害。