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来自湖北凤仙花变种根茎的三种新三萜皂苷。

Three new triterpenoid saponins from the rhizomes of Impatiens pritzellii var. hupehensis.

作者信息

Zhou X-F, Zhao X-Y, Tang L, Ruan H-L, Zhang Y-H, Pi H-F, Xiao W-L, Sun H-D, Wu J-Z

机构信息

Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China.

出版信息

J Asian Nat Prod Res. 2007 Apr-Aug;9(3-5):379-85. doi: 10.1080/10286020600781019.

Abstract

Three new triterpenoid saponins, impatiprins A-C (1-3), together with a known triterpenoid (4) and two known triterpenoid saponins (5, 6), were isolated from the rhizomes of Impatiens pritzellii Hook. f. var. hupehensis Hook. f. The structures of 1-3 were determined by 1D and 2D NMR, FAB-MS techniques and chemical methods. Compounds 1 and 2 showed weak cytotoxicities against S-180, HeLa and HepG2 cell lines.

摘要

从湖北凤仙花(Impatiens pritzellii Hook. f. var. hupehensis Hook. f.)的根茎中分离得到了3个新的三萜皂苷,凤仙皂苷A-C(1-3),以及1个已知的三萜(4)和2个已知的三萜皂苷(5, 6)。通过一维和二维核磁共振、快原子轰击质谱技术及化学方法确定了1-3的结构。化合物1和2对S-180、HeLa和HepG2细胞系显示出较弱的细胞毒性。

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