一名患有心内膜炎患者体内一株对达托霉素不敏感的万古霉素中介金黄色葡萄球菌菌株的特征分析。
Characterization of a daptomycin-nonsusceptible vancomycin-intermediate Staphylococcus aureus strain in a patient with endocarditis.
作者信息
Julian Kathleen, Kosowska-Shick Klaudia, Whitener Cynthia, Roos Martin, Labischinski Harald, Rubio Aileen, Parent Leslie, Ednie Lois, Koeth Laura, Bogdanovich Tatiana, Appelbaum Peter C
机构信息
Penn State Milton S. Hershey Medical Center, Room C6833, BMR Bldg., Mailcode H036, 500 University Dr., Hershey, PA 17033, USA.
出版信息
Antimicrob Agents Chemother. 2007 Sep;51(9):3445-8. doi: 10.1128/AAC.00559-07. Epub 2007 Jul 9.
Abstract
We analyzed the emergence of daptomycin nonsusceptibility in a patient with persistent vancomycin-intermediate Staphylococcus aureus (VISA) bacteremia. The daptomycin-nonsusceptible VISA's cell wall demonstrated a reduction in muramic acid O-acetylation, a phenotypic parameter not previously reported for VISA; some isolates also contained a single point mutation in the mprF gene.
摘要
我们分析了一名患有持续性万古霉素中介金黄色葡萄球菌（VISA）菌血症患者中达托霉素不敏感情况的出现。达托霉素不敏感的VISA的细胞壁显示出胞壁酸O-乙酰化减少，这是一个此前未在VISA中报道过的表型参数；一些分离株在mprF基因中还存在单点突变。
相似文献
1
Characterization of a daptomycin-nonsusceptible vancomycin-intermediate Staphylococcus aureus strain in a patient with endocarditis.一名患有心内膜炎患者体内一株对达托霉素不敏感的万古霉素中介金黄色葡萄球菌菌株的特征分析。
Antimicrob Agents Chemother. 2007 Sep;51(9):3445-8. doi: 10.1128/AAC.00559-07. Epub 2007 Jul 9.
2
Daptomycin nonsusceptibility in Staphylococcus aureus with reduced vancomycin susceptibility is independent of alterations in MprF.对万古霉素敏感性降低的金黄色葡萄球菌中达托霉素不敏感性与MprF的改变无关。
Antimicrob Agents Chemother. 2007 Jun;51(6):2223-5. doi: 10.1128/AAC.00202-07. Epub 2007 Apr 2.
3
Bacteremia and infective endocarditis caused by a non-daptomycin-susceptible, vancomycin-intermediate, and methicillin-resistant Staphylococcus aureus strain in Taiwan.台湾地区一株对达托霉素不敏感、对万古霉素中介且耐甲氧西林的金黄色葡萄球菌引起的菌血症和感染性心内膜炎
J Clin Microbiol. 2008 Mar;46(3):1132-6. doi: 10.1128/JCM.01844-07. Epub 2008 Jan 16.
4
Occurrence of a USA300 vancomycin-intermediate Staphylococcus aureus.一株USA300万古霉素中介金黄色葡萄球菌的出现。
Diagn Microbiol Infect Dis. 2008 Dec;62(4):440-2. doi: 10.1016/j.diagmicrobio.2008.08.005. Epub 2008 Oct 7.
5
Activities of antistaphylococcal antibiotics towards the extracellular and intraphagocytic forms of Staphylococcus aureus isolates from a patient with persistent bacteraemia and endocarditis.抗葡萄球菌抗生素对一名患有持续性菌血症和心内膜炎患者分离出的金黄色葡萄球菌细胞外及吞噬细胞内形式的活性。
Clin Microbiol Infect. 2008 Aug;14(8):766-77. doi: 10.1111/j.1469-0691.2008.02035.x.
6
Perspectives on Daptomycin resistance, with emphasis on resistance in Staphylococcus aureus.达托霉素耐药性的观点，重点关注金黄色葡萄球菌的耐药性。
Clin Infect Dis. 2007 Sep 1;45(5):601-8. doi: 10.1086/520655. Epub 2007 Aug 1.
7
Serial daptomycin selection generates daptomycin-nonsusceptible Staphylococcus aureus strains with a heterogeneous vancomycin-intermediate phenotype.连续使用达托霉素进行筛选会产生具有异质性万古霉素中介表型的对达托霉素不敏感的金黄色葡萄球菌菌株。
Antimicrob Agents Chemother. 2008 Dec;52(12):4289-99. doi: 10.1128/AAC.00417-08. Epub 2008 Sep 29.
8
Emergence of a clinical daptomycin-resistant Staphylococcus aureus isolate during treatment of methicillin-resistant Staphylococcus aureus bacteremia and osteomyelitis.在耐甲氧西林金黄色葡萄球菌菌血症和骨髓炎治疗期间出现临床耐达托霉素金黄色葡萄球菌分离株。
J Clin Microbiol. 2006 Feb;44(2):595-7. doi: 10.1128/JCM.44.2.595-597.2006.
9
Diminished vancomycin and daptomycin susceptibility during prolonged bacteremia with methicillin-resistant Staphylococcus aureus.耐甲氧西林金黄色葡萄球菌长期菌血症期间万古霉素和达托霉素敏感性降低
Diagn Microbiol Infect Dis. 2008 Apr;60(4):437-40. doi: 10.1016/j.diagmicrobio.2007.11.002. Epub 2007 Dec 21.
10
Daptomycin non-susceptibility in vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous-VISA (hVISA): implications for therapy after vancomycin treatment failure.万古霉素中介金黄色葡萄球菌（VISA）和异质性万古霉素中介金黄色葡萄球菌（hVISA）中的达托霉素不敏感性：万古霉素治疗失败后治疗的影响。
J Antimicrob Chemother. 2011 May;66(5):1057-60. doi: 10.1093/jac/dkr066. Epub 2011 Mar 2.
引用本文的文献
1
MprF from is a promiscuous lipid scramblase with broad substrate specificity.来自[具体来源未给出]的MprF是一种具有广泛底物特异性的混杂脂质翻转酶。
Sci Adv. 2025 Apr 11;11(15):eads9135. doi: 10.1126/sciadv.ads9135. Epub 2025 Apr 9.
2
Population Analysis of Daptomycin-non-Susceptible Methicillin-Resistant Staphylococcus aureus Reveals the Presence of Variants That Contribute to Daptomycin Resistance.对达托霉素不敏感的耐甲氧西林金黄色葡萄球菌的种群分析揭示了导致达托霉素耐药的变异体的存在。
Curr Microbiol. 2024 Jan 11;81(2):61. doi: 10.1007/s00284-023-03579-4.
3
Bacterial cell membranes and their role in daptomycin resistance: A review.细菌细胞膜及其在达托霉素耐药性中的作用：综述
Front Mol Biosci. 2022 Nov 14;9:1035574. doi: 10.3389/fmolb.2022.1035574. eCollection 2022.
4
Genome-Wide Association Studies for the Detection of Genetic Variants Associated With Daptomycin and Ceftaroline Resistance in .全基因组关联研究用于检测与达托霉素和头孢洛林耐药性相关的基因变异 。 （原文句子不完整，推测补充完整后大概是这样的意思，你可根据实际情况进行调整）
Front Microbiol. 2021 Feb 15;12:639660. doi: 10.3389/fmicb.2021.639660. eCollection 2021.
5
Single nucleotide polymorphism leads to daptomycin resistance causing amino acid substitution-T345I in MprF of clinically isolated MRSA strains.单核苷酸多态性导致达托霉素耐药，导致临床分离的耐甲氧西林金黄色葡萄球菌菌株 mprf 中的氨基酸取代-T345I。
PLoS One. 2021 Jan 22;16(1):e0245732. doi: 10.1371/journal.pone.0245732. eCollection 2021.
6
Clinical Pharmacokinetics of Daptomycin.达托霉素的临床药代动力学。
Clin Pharmacokinet. 2021 Mar;60(3):271-281. doi: 10.1007/s40262-020-00968-x. Epub 2020 Dec 14.
7
Global prevalence and distribution of vancomycin resistant, vancomycin intermediate and heterogeneously vancomycin intermediate Staphylococcus aureus clinical isolates: a systematic review and meta-analysis.万古霉素耐药、万古霉素中介和异质性万古霉素中介金黄色葡萄球菌临床分离株的全球流行率和分布：系统评价和荟萃分析。
Sci Rep. 2020 Jul 29;10(1):12689. doi: 10.1038/s41598-020-69058-z.
8
Metabolic changes associated with adaptive resistance to daptomycin in Streptococcus mitis-oralis.与屎肠球菌-口腔链球菌对达托霉素适应性耐药相关的代谢变化。
BMC Microbiol. 2020 Jun 15;20(1):162. doi: 10.1186/s12866-020-01849-w.
9
Effect of a Point Mutation in on Susceptibility to Daptomycin, Vancomycin, and Oxacillin in an MRSA Clinical Strain.耐甲氧西林金黄色葡萄球菌临床菌株中某点突变对达托霉素、万古霉素和苯唑西林敏感性的影响
Front Microbiol. 2018 May 25;9:1086. doi: 10.3389/fmicb.2018.01086. eCollection 2018.
10
Impact of Bacterial Membrane Fatty Acid Composition on the Failure of Daptomycin To Kill Staphylococcus aureus.细菌膜脂肪酸组成对达托霉素杀灭金黄色葡萄球菌失败的影响。
Antimicrob Agents Chemother. 2018 Jun 26;62(7). doi: 10.1128/AAC.00023-18. Print 2018 Jul.
本文引用的文献
1
Daptomycin nonsusceptibility in Staphylococcus aureus with reduced vancomycin susceptibility is independent of alterations in MprF.对万古霉素敏感性降低的金黄色葡萄球菌中达托霉素不敏感性与MprF的改变无关。
Antimicrob Agents Chemother. 2007 Jun;51(6):2223-5. doi: 10.1128/AAC.00202-07. Epub 2007 Apr 2.
2
A multicenter study evaluating the current strategies for isolating Staphylococcus aureus strains with reduced susceptibility to glycopeptides.一项评估当前分离对糖肽类药物敏感性降低的金黄色葡萄球菌菌株策略的多中心研究。
J Clin Microbiol. 2007 Feb;45(2):329-32. doi: 10.1128/JCM.01508-06. Epub 2006 Nov 15.
3
Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus.达托霉素与标准疗法治疗金黄色葡萄球菌引起的菌血症和心内膜炎的比较。
N Engl J Med. 2006 Aug 17;355(7):653-65. doi: 10.1056/NEJMoa053783.
4
The activity of daptomycin against wild-type Staphylococcus aureus and strains with reduced susceptibility to vancomycin.达托霉素对野生型金黄色葡萄球菌及对万古霉素敏感性降低菌株的活性。
Clin Infect Dis. 2006 Sep 15;43(6):798-9; author reply 799-800. doi: 10.1086/507109.
5
Genetic changes that correlate with reduced susceptibility to daptomycin in Staphylococcus aureus.与金黄色葡萄球菌对达托霉素敏感性降低相关的基因变化。
Antimicrob Agents Chemother. 2006 Jun;50(6):2137-45. doi: 10.1128/AAC.00039-06.
6
An association between reduced susceptibility to daptomycin and reduced susceptibility to vancomycin in Staphylococcus aureus.金黄色葡萄球菌中对达托霉素敏感性降低与对万古霉素敏感性降低之间的关联。
Clin Infect Dis. 2006 Jun 1;42(11):1652-3. doi: 10.1086/504084.
7
Correlation between Reduced Daptomycin Susceptibility and Vancomycin Resistance in Vancomycin-Intermediate Staphylococcus aureus.万古霉素中度敏感金黄色葡萄球菌中达托霉素敏感性降低与万古霉素耐药性之间的相关性
Antimicrob Agents Chemother. 2006 Mar;50(3):1079-82. doi: 10.1128/AAC.50.3.1079-1082.2006.
8
Single- and multistep resistance selection studies on the activity of retapamulin compared to other agents against Staphylococcus aureus and Streptococcus pyogenes.与其他药物相比，瑞他帕林对金黄色葡萄球菌和化脓性链球菌活性的单步和多步耐药性选择研究。
Antimicrob Agents Chemother. 2006 Feb;50(2):765-9. doi: 10.1128/AAC.50.2.765-769.2006.
9
Clinical progression of methicillin-resistant Staphylococcus aureus vertebral osteomyelitis associated with reduced susceptibility to daptomycin.耐甲氧西林金黄色葡萄球菌性脊椎骨髓炎的临床进展与对达托霉素敏感性降低相关
J Clin Microbiol. 2005 Oct;43(10):5384-7. doi: 10.1128/JCM.43.10.5384-5387.2005.
10
Development of Daptomycin resistance in vivo in methicillin-resistant Staphylococcus aureus.耐甲氧西林金黄色葡萄球菌体内达托霉素耐药性的产生
J Clin Microbiol. 2005 Oct;43(10):5285-7. doi: 10.1128/JCM.43.10.5285-5287.2005.
Zotero 插件