McNab Alan A
Orbital Plastic and Lacrimal Clinic, Royal Victorian Eye and Ear Hospital, East Melbourne, 3002 Vic., Australia.
Sleep Med Rev. 2007 Aug;11(4):269-76. doi: 10.1016/j.smrv.2007.03.006.
Several eye disorders have been found in association with obstructive sleep apnea (OSA). This paper reviews the current state of knowledge of eye disorders associated with OSA. OSA is associated with a number of eye disorders including floppy eyelid syndrome (FES), optic neuropathy, glaucoma, non-arteritic anterior ischemic optic neuropathy and papilledema secondary to raised intracranial pressure. FES patients have a very high incidence of OSA and a causal relationship may exist, but amongst patients with OSA, FES is uncommon but commoner than in the general population. Treatment of OSA may help floppy eyelid syndrome, halt progression of associated glaucoma or optic neuropathy, and reduce intracranial pressure in patients with associated papilledema. Sleep apnea patients should be asked about ocular symptoms and appropriately examined or referred for assessment as some of the associated eye disorders may permanently impair vision. Ophthalmologists should be aware of the association of sleep apnea with these eye disorders and consider referral to a sleep physician for investigation and possible treatment.
已发现几种眼部疾病与阻塞性睡眠呼吸暂停(OSA)有关。本文综述了与OSA相关的眼部疾病的当前知识状况。OSA与多种眼部疾病有关,包括眼睑松弛综合征(FES)、视神经病变、青光眼、非动脉性前部缺血性视神经病变以及继发于颅内压升高的视乳头水肿。FES患者中OSA的发病率非常高,可能存在因果关系,但在OSA患者中,FES并不常见,但比一般人群更常见。治疗OSA可能有助于眼睑松弛综合征,阻止相关青光眼或视神经病变的进展,并降低伴有视乳头水肿患者的颅内压。应询问睡眠呼吸暂停患者的眼部症状,并进行适当检查或转诊进行评估,因为一些相关的眼部疾病可能会永久性损害视力。眼科医生应了解睡眠呼吸暂停与这些眼部疾病的关联,并考虑转诊至睡眠科医生进行检查和可能的治疗。