Wu Lihteh, Velasquez Roberto, Montoya Olga
Instituto de Cirugía Ocular, Apdo 144-1225 Plaza Mayor, San Jose, Costa Rica.
Int Ophthalmol. 2008 Apr;28(2):89-93. doi: 10.1007/s10792-007-9119-9. Epub 2007 Jul 19.
The visualization of the anterior lens capsule is greatly enhanced by trypan blue staining facilitating the creation of a continuous curvilinear capsulorhexis. Trypan blue has been deemed safe in this setting.
We report the findings and management of a retrospective interventional case series comprising three eyes that developed non-infectious endophthalmitis following routine trypan blue staining of the anterior lens capsule with the same batch of Vission (0.6 mg/ml) during uncomplicated small incision phacoemulsification of 17 consecutive eyes.
On post-op day 1, 18% had an increased cellular response in the anterior chamber and anterior vitreous precluding fundus visualization, 12% had a hypopyon. Initial visual acuity (VA) ranged from hand motions to light perception. Eyes were initially managed with topical and oral steroids. Two eyes underwent vitrectomy. Vitreous cultures were all negative. One eye had a repeat vitrectomy to remove an epiretinal membrane. Final VA achieved was 20/80, 20/20 and 20/20.
Trypan blue may be associated with severe intraocular inflammation.
锥蓝染色可显著增强晶状体前囊的可视化效果，有助于制作连续的环形撕囊。在这种情况下，锥蓝被认为是安全的。
我们报告了一个回顾性干预病例系列的结果及处理情况，该系列包括三只眼睛，这三只眼睛在连续17只眼睛的简单小切口白内障超声乳化手术中，使用同一批次的Vission（0.6毫克/毫升）对晶状体前囊进行常规锥蓝染色后发生了非感染性眼内炎。
术后第1天，18%的患者前房和前部玻璃体的细胞反应增加，妨碍了眼底观察，12%的患者出现前房积脓。初始视力范围从手动到光感。最初对眼睛采用局部和口服类固醇治疗。两只眼睛接受了玻璃体切除术。玻璃体培养均为阴性。一只眼睛再次进行玻璃体切除术以清除视网膜前膜。最终达到的视力分别为20/80、20/20和20/20。
锥蓝可能与严重的眼内炎症有关。
