Hormonal regulation of fatty acid synthesis in adipose tissue through changes in the activities of pyruvate dehydrogenase (EC 1.2.4.1) and acetyl-CoA carboxylase (EC 6.4.1.2).
作者信息
Denton R M
出版信息
Proc Nutr Soc. 1975 Dec;34(3):217-24. doi: 10.1079/pns19750042.
PMID:1764
Abstract
摘要
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Hormonal regulation of fatty acid synthesis in adipose tissue through changes in the activities of pyruvate dehydrogenase (EC 1.2.4.1) and acetyl-CoA carboxylase (EC 6.4.1.2).通过丙酮酸脱氢酶（EC 1.2.4.1）和乙酰辅酶A羧化酶（EC 6.4.1.2）活性的变化对脂肪组织中脂肪酸合成进行激素调节。
Proc Nutr Soc. 1975 Dec;34(3):217-24. doi: 10.1079/pns19750042.
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Evidence that fatty acid synthesis in the interscapular brown adipose tissue of cold-adapted rats is increased in vivo by insulin by mechanisms involving parallel activation of pyruvate dehydrogenase and acetyl-coenzyme A carboxylase.有证据表明，在冷适应大鼠的肩胛间棕色脂肪组织中，脂肪酸合成在体内会因胰岛素而增加，其机制涉及丙酮酸脱氢酶和乙酰辅酶A羧化酶的平行激活。
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The regulation of fatty acid synthesis in brown adipose tissue by insulin.胰岛素对棕色脂肪组织中脂肪酸合成的调节。
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The role of phosphorylation in the regulation of fatty acid synthesis by insulin and other hormones.磷酸化在胰岛素及其他激素对脂肪酸合成的调节中的作用。
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Lipogenic enzymes in rat maternal adipose tissue in the perinatal period.围产期大鼠母体脂肪组织中的生脂酶
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Persistence of the effect of insulin on pyruvate dehydrogenase activity in rat white and brown adipose tissue during the preparation and subsequent incubation of mitochondria.在制备大鼠白色和棕色脂肪组织线粒体及随后的孵育过程中，胰岛素对丙酮酸脱氢酶活性的影响持续存在。
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Biochem J. 1977 Sep 15;166(3):627-30. doi: 10.1042/bj1660627.
6
Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats.抗胰岛素血清对喂食大鼠肝脏和附睾脂肪组织中脂肪酸合成速率、乙酰辅酶A羧化酶及丙酮酸脱氢酶活性的体内急性效应
Biochem J. 1976 Nov 15;160(2):413-6. doi: 10.1042/bj1600413.
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