Kang Chi-Chih, Chang Cheng-Chung, Chang Ta-Chau, Liao Li-Jen, Lou Pei-Jen, Xie Wenjun, Yeung Edward S
Institute of Atomic and Molecular Sciences, Academia Sinica, P.O. Box 23-166, Taipei, Taiwan 106, Republic of China.
Analyst. 2007 Aug;132(8):745-9. doi: 10.1039/b617733f. Epub 2007 Jun 8.
A simple handheld device based on the fluorescence analysis of 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide (BMVC) stained cells was established for routine screening and potentially for early detection of cancer cells at extremely low cost. Flow cytometry assay further supported the utility of this simple device, where a preliminary study of tissue biopsy showed highly encouraging results.
基于对3,6-双(1-甲基-4-乙烯基吡啶鎓)咔唑二碘化物(BMVC)染色细胞进行荧光分析的一种简单手持设备被开发出来,用于常规筛查,并有可能以极低的成本早期检测癌细胞。流式细胞术分析进一步证实了这种简单设备的实用性,对组织活检的初步研究显示出非常令人鼓舞的结果。