Anderson John R, Byrne Dana, Fincham Jon M, Gunn Pat
Psychology Department, Carnegie Mellon University, Pittsburgh, PA 15213, USA. ja+@cmu.edu
Cereb Cortex. 2008 Apr;18(4):904-14. doi: 10.1093/cercor/bhm123. Epub 2007 Aug 3.
Two studies were performed that compared a "Paired" condition in which participants studied paired associates with a "Generated" condition in which participants completed word fragments to produce paired associates. In both tasks, participants were responsible for memory of the material either studied or generated. The experiments revealed significant differences between the responses of a predefined prefrontal region and a predefined parietal region. The parietal region responded more in the Generated condition than the Paired condition, whereas there was no difference in the prefrontal region. On the other hand, the prefrontal region responded to the delay between study and test in both the Paired and Generated conditions, whereas the parietal region only responded to delay in the Generated condition. This pattern of results is consistent with the hypothesis that the parietal region is responsive to changes in problem representation and the prefrontal region to retrieval operations. An information-processing model embodying these assumptions was fit to the blood oxygen level-dependent responses in these regions.
进行了两项研究，比较了“配对”条件（参与者学习配对联想词）和“生成”条件（参与者完成单词片段以生成配对联想词）。在这两项任务中，参与者都要负责记忆所学习或生成的材料。实验揭示了一个预定义的前额叶区域和一个预定义的顶叶区域的反应之间存在显著差异。顶叶区域在“生成”条件下的反应比“配对”条件下更多，而前额叶区域则没有差异。另一方面，前额叶区域在“配对”和“生成”条件下对学习和测试之间的延迟都有反应，而顶叶区域仅在“生成”条件下对延迟有反应。这种结果模式与以下假设一致，即顶叶区域对问题表征的变化有反应，而前额叶区域对检索操作有反应。一个体现这些假设的信息处理模型与这些区域的血氧水平依赖反应相拟合。
