肠道细菌中四种氨酰基转移核糖核酸合成酶的生长速率调节
Growth rate modulation of four aminoacyl-transfer ribonucleic acid synthetases in enteric bacteria.
作者信息
McKeever W G, Neidhardt F C
出版信息
J Bacteriol. 1976 May;126(2):634-45. doi: 10.1128/jb.126.2.634-645.1976.
Abstract
The specific activities of arginyl- glutamyl- seryl-, and valyl-transfer ribonucleic acid (tRNA) synthetases were measured in the wild-type and mutant strains of Salmonella typhimurium LT2 and Escherichia coli B/r. In media restricted only by carbon and energy source availability, the specific activities of all four enzymes were proportional to the growth rate, with the exception of seryl-tRNA synthetase in S. typhimurium, which remained essentially constant. Structural gene densities were calculated for these four enzymes and were found not to account for the variation of specific activity with growth rate.
摘要
测定了鼠伤寒沙门氏菌LT2和大肠杆菌B/r野生型及突变株中精氨酰 - 谷氨酰 - 丝氨酰 - 和缬氨酰 - 转移核糖核酸（tRNA）合成酶的比活性。在仅受碳源和能源可用性限制的培养基中，除鼠伤寒沙门氏菌中的丝氨酰 - tRNA合成酶基本保持恒定外，所有四种酶的比活性均与生长速率成正比。计算了这四种酶的结构基因密度，发现其不能解释比活性随生长速率的变化。
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