Harrus Shimon, Bar-Gal Gilla Kahila, Golan Amira, Elazari-Volcani Ron, Kosoy Michael Y, Morick Danny, Avidor Boaz, Baneth Gad
Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel.
Am J Trop Med Hyg. 2009 Jul;81(1):55-8.
Ten Bartonella isolates were cultured from blood drawn from black rats (Rattus rattus) captured in the Tel Aviv area. Genetic characterization included amplification and sequencing of five gene fragments including the ribC, rpoB, 16S, groEL, and gltA and the 16S-23S intergenic spacer region. Sequence comparisons showed that all 10 isolates were identical in all genes studied comprising a total of 3,873 bp analyzed. The sequences of each of the partial genes analyzed indicated a high sequence similarity (97-99.8%) to B. tribocorum or B. elizabethae. The gltA sequence was 100% homologous to a genotype identified in R. rattus in Dhaka, Bangladesh, suggesting the existence of a widespread Asian Bartonella strain infecting the black rats (R. rattus). The detection of a Bartonella genotype closely related to B. elizabethae in the biggest metropolitan center in Israel warrants further study of its zoonotic potential and pathogenic characteristics.
从特拉维夫地区捕获的黑鼠（褐家鼠）血液中培养出了10株巴尔通体分离株。基因特征分析包括对五个基因片段进行扩增和测序，这五个基因片段分别是ribC、rpoB、16S、groEL和gltA以及16S - 23S基因间隔区。序列比较显示，在总共分析的3873 bp的所有研究基因中，所有10株分离株都是相同的。所分析的每个部分基因的序列与三氏巴尔通体或伊丽莎白巴尔通体显示出高度的序列相似性（97 - 99.8%）。gltA序列与在孟加拉国达卡的褐家鼠中鉴定出的一种基因型100%同源，这表明存在一种广泛传播的感染黑鼠（褐家鼠）的亚洲巴尔通体菌株。在以色列最大的大都市中心检测到与伊丽莎白巴尔通体密切相关的巴尔通体基因型，有必要进一步研究其人畜共患病潜力和致病特征。
