Science. 1970 Dec 18;170(3964):1310-3. doi: 10.1126/science.170.3964.1310.
On the basis of estimates of molecular damage caused by the observation process, it is concluded that molecular microscopy of biological molecules in which the individual atoms are resolved is impossible with an electron or x-ray microscope. Microscopes that use low-energy helium atoms or neutrons as illuminants may be capable of serving as ultimate biomolecular microscopes.
基于观察过程中分子损伤的估计，得出结论，使用电子或 X 射线显微镜不可能对单个原子分辨率的生物分子进行分子显微镜观察。使用低能氦原子或中子作为照明物的显微镜可能有能力成为最终的生物分子显微镜。
