• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Regulation by thyroid hormone of microtubule assembly and neuronal differentiation.

作者信息

Nunez J, Couchie D, Aniello F, Bridoux A M

机构信息

INSERM U 282-CNRS, Hôpital Henri Mondor, Créteil, France.

出版信息

Neurochem Res. 1991 Sep;16(9):975-82. doi: 10.1007/BF00965840.

DOI:10.1007/BF00965840
PMID:1784340
Abstract

In this review we examine successively: 1) the major effects of thyroid hormone deficiency seen during brain development with special emphasis on the changes in neuronal morphology and migration occurring postnatally in the cerebellum. 2) The effects of this hormone on microtubule assembly during neurite outgrowth and acquisition of neuronal polarity. 3) The changes in expression of the different tubulin isoforms occurring during development in the normal and hypothyroid rat brain. 4) The regulation by thyroid hormone of the transition occurring during development between the juvenile and adult microtubule-associated protein Tau.

摘要

相似文献

1
Regulation by thyroid hormone of microtubule assembly and neuronal differentiation.
Neurochem Res. 1991 Sep;16(9):975-82. doi: 10.1007/BF00965840.
2
Thyroid hormone effects on neuronal differentiation during brain development.甲状腺激素对大脑发育过程中神经元分化的影响。
Acta Med Austriaca. 1992;19 Suppl 1:36-9.
3
Microtubules and brain development: The effects of thyroid hormones.
Neurochem Int. 1985;7(6):959-68. doi: 10.1016/0197-0186(85)90144-5.
4
Thyroid hormones and neurotubule assembly in vitro during brain development.
Eur J Biochem. 1979 Nov;101(2):365-76. doi: 10.1111/j.1432-1033.1979.tb19728.x.
5
Splicing of juvenile and adult tau mRNA variants is regulated by thyroid hormone.青少年和成人tau mRNA变体的剪接受甲状腺激素调节。
Proc Natl Acad Sci U S A. 1991 May 1;88(9):4035-9. doi: 10.1073/pnas.88.9.4035.
6
Microtubule stability and MAP1B upregulation control neuritogenesis in CAD cells.微管稳定性和MAP1B上调调控CAD细胞中的神经突形成。
Acta Pharmacol Sin. 2006 Sep;27(9):1119-26. doi: 10.1111/j.1745-7254.2006.00362.x.
7
Tubulin synthesis and assembly in differentiating neurons.分化神经元中的微管蛋白合成与组装
Biochem Cell Biol. 1997;75(2):103-17.
8
The initiation of neurite outgrowth by sympathetic neurons grown in vitro does not depend on assembly of microtubules.体外培养的交感神经元神经突生长的起始并不依赖于微管的组装。
J Cell Biol. 1994 Dec;127(5):1407-18. doi: 10.1083/jcb.127.5.1407.
9
Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors.神经生长因子诱导PC12细胞的神经突生长涉及微管组装和组装促进因子的协同诱导。
J Cell Biol. 1985 Nov;101(5 Pt 1):1799-807. doi: 10.1083/jcb.101.5.1799.
10
Expression of the class III beta-tubulin isotype in developing neurons in culture.III类β-微管蛋白亚型在培养的发育中神经元中的表达。
J Neurosci Res. 1992 Aug;32(4):516-29. doi: 10.1002/jnr.490320407.

引用本文的文献

1
Involvement of Thyroid Hormones in Brain Development and Cancer.甲状腺激素在脑发育和癌症中的作用。
Cancers (Basel). 2021 May 30;13(11):2693. doi: 10.3390/cancers13112693.
2
An evo-devo approach to thyroid hormones in cerebral and cerebellar cortical development: etiological implications for autism.从演化发育角度探讨甲状腺激素对大脑和小脑皮质发育的影响：自闭症的病因学意义。
Front Endocrinol (Lausanne). 2014 Sep 9;5:146. doi: 10.3389/fendo.2014.00146. eCollection 2014.
3
Chronic perchlorate exposure impairs stickleback reproductive behaviour and swimming performance.

本文引用的文献

1
Microtubules and neurofilaments in the sciatic nerve fibres of the developing rat: Effects of thyroid deficiency.
Int J Dev Neurosci. 1985;3(4):353-8. doi: 10.1016/0736-5748(85)90069-3.
2
Microtubules and brain development: The effects of thyroid hormones.
Neurochem Int. 1985;7(6):959-68. doi: 10.1016/0197-0186(85)90144-5.
3
Rat, mouse, and guinea pig brain development and microtubule assembly.大鼠、小鼠和豚鼠的脑发育与微管组装。
J Neurochem. 1980 Oct;35(4):804-13. doi: 10.1111/j.1471-4159.1980.tb07076.x.
4
长期暴露于高氯酸盐会损害棘鱼的繁殖行为和游泳能力。
Behaviour. 2008;145(4-5):537-559. doi: 10.1163/156853908792451511.
4
Non-genomic actions of thyroid hormone in brain development.甲状腺激素在脑发育中的非基因组作用。
Steroids. 2008 Oct;73(9-10):1008-12. doi: 10.1016/j.steroids.2007.12.016. Epub 2007 Dec 27.
5
Retinoid-related orphan receptor alpha controls the early steps of Purkinje cell dendritic differentiation.类视黄醇相关孤儿受体α控制浦肯野细胞树突分化的早期步骤。
J Neurosci. 2006 Feb 1;26(5):1531-8. doi: 10.1523/JNEUROSCI.4636-05.2006.
6
Action of thyroid hormone in brain.甲状腺激素在大脑中的作用。
J Endocrinol Invest. 2002 Mar;25(3):268-88. doi: 10.1007/BF03344003.
7
Silencing of Wnt signaling and activation of multiple metabolic pathways in response to thyroid hormone-stimulated cell proliferation.响应甲状腺激素刺激的细胞增殖，Wnt信号通路的沉默及多种代谢途径的激活。
Mol Cell Biol. 2001 Oct;21(19):6626-39. doi: 10.1128/MCB.21.19.6626-6639.2001.
8
Thyroidal dysfunction and environmental chemicals--potential impact on brain development.甲状腺功能障碍与环境化学物质——对大脑发育的潜在影响。
Environ Health Perspect. 2000 Jun;108 Suppl 3(Suppl 3):433-8. doi: 10.1289/ehp.00108s3433.
Changes in composition and activity of microtubule-associated proteins during brain development.脑发育过程中微管相关蛋白的组成与活性变化
Nature. 1980 Mar 27;284(5754):353-5. doi: 10.1038/284353a0.
5
Heterogeneity of microtubule-associated proteins and brain development.微管相关蛋白的异质性与脑发育
Eur J Biochem. 1982 Dec 15;129(2):465-71. doi: 10.1111/j.1432-1033.1982.tb07072.x.
6
Effects of thyroid state and undernutrition on S100 protein and astroglia development in rat cerebellum.甲状腺状态和营养不足对大鼠小脑S100蛋白及星形胶质细胞发育的影响。
Dev Neurosci. 1982 Mar-Jun;5(2-3):285-92. doi: 10.1159/000112687.
7
Differential subcellular localization of tubulin and the microtubule-associated protein MAP2 in brain tissue as revealed by immunocytochemistry with monoclonal hybridoma antibodies.利用单克隆杂交瘤抗体进行免疫细胞化学分析，揭示了脑组织中微管蛋白和微管相关蛋白MAP2在亚细胞水平上的差异定位。
J Neurosci. 1984 Feb;4(2):394-410. doi: 10.1523/JNEUROSCI.04-02-00394.1984.
8
Differential distribution of microtubule-associated proteins MAP-1 and MAP-2 in neurons of rat brain and association of MAP-1 with microtubules of neuroblastoma cells (clone N2A).大鼠脑神经元中微管相关蛋白MAP-1和MAP-2的差异分布以及MAP-1与神经母细胞瘤细胞（克隆N2A）微管的关联。
EMBO J. 1983;2(11):1915-20. doi: 10.1002/j.1460-2075.1983.tb01679.x.
9
Studies on the expression of the microtubule-associated protein, tau, during mouse brain development, with newly isolated complementary DNA probes.利用新分离的互补DNA探针，对小鼠大脑发育过程中微管相关蛋白tau的表达进行研究。
J Cell Biol. 1984 Mar;98(3):1090-7. doi: 10.1083/jcb.98.3.1090.
10
Distribution of microtubule-associated protein 2 in the nervous system of the rat studied by immunofluorescence.用免疫荧光法研究大鼠神经系统中微管相关蛋白2的分布。
Neuroscience. 1984 Apr;11(4):817-46.