随着肝性脑病的改善，白质病变体积减小。
Decrease in the volume of white matter lesions with improvement of hepatic encephalopathy.
作者信息
Mínguez B, Rovira A, Alonso J, Córdoba J
机构信息
Servicio de Medicina Interna-Hepatología, Hospital Universitario Valle Hebron, Departament de Medicina, Universitat Autònoma de Barcelona, Barcelona Spain.
出版信息
AJNR Am J Neuroradiol. 2007 Sep;28(8):1499-500. doi: 10.3174/ajnr.A0611.
Abstract
MR imaging has found abnormalities compatible with low-grade edema in the brain of patients with cirrhosis that have been related to hepatic encephalopathy. We present 3 patients with hepatic encephalopathy who exhibit supratentorial focal or diffuse white matter lesions compatible with small-vessel brain disease. The volume and number of white matter lesions reduced with the improvement of hepatic encephalopathy, suggesting the participation of the blood-brain barrier in the pathogenesis of brain edema in hepatic encephalopathy.
摘要
磁共振成像已在肝硬化患者大脑中发现与轻度水肿相符的异常，这些异常与肝性脑病有关。我们报告3例肝性脑病患者，其幕上出现与小血管性脑疾病相符的局灶性或弥漫性白质病变。随着肝性脑病的改善，白质病变的体积和数量减少，提示血脑屏障参与了肝性脑病脑水肿的发病机制。
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