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异靛酮A和B,来自宽叶菘蓝的新型抗真菌氧化吲哚生物碱。

Isatinones A and B, new antifungal oxindole alkaloids from Isatis costata.

作者信息

Fatima Itrat, Ahmad Ijaz, Anis Itrat, Malik Abdul, Afza Nighat

机构信息

International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.

出版信息

Molecules. 2007 Feb 6;12(2):155-62. doi: 10.3390/12020155.

DOI:10.3390/12020155
PMID:17846565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6149419/
Abstract

Two new oxindole alkaloids isatinone A (1) and B (2) have been isolated from Isatis costata, along with the known trisindoline. Their structures have been assigned on the basis of spectroscopic techniques and chemical studies. Both new compounds showed significant antifungal activity.

摘要

从菘蓝中分离出两种新的氧化吲哚生物碱异吲哚酮A(1)和B(2),以及已知的三吲哚啉。它们的结构已通过光谱技术和化学研究确定。这两种新化合物均表现出显著的抗真菌活性。

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本文引用的文献

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A tandem Heck-carbocyclization/Suzuki-coupling approach to the stereoselective syntheses of asymmetric 3,3-(diarylmethylene)indolinones.一种串联Heck-碳环化/铃木偶联方法用于立体选择性合成不对称3,3-(二芳基亚甲基)吲哚啉酮。
J Org Chem. 2005 Apr 29;70(9):3741-4. doi: 10.1021/jo050016d.
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Antifungal steroidal lactones from Withania coagulance.来自凝乳状睡茄的抗真菌甾体内酯。
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