Isii Youzou, Matsukawa Kanji, Tsuchimochi Hirotsugu, Nakamoto Tomoko
Department of Physiology, Graduate School of Health Sciences, Hiroshima University, Hiroshima, 734-8551 Japan.
J Physiol Sci. 2007 Aug;57(4):241-8. doi: 10.2170/physiolsci.RP007707. Epub 2007 Sep 15.
Cutaneous receptors stimulated by ice-water immersion of one hand will increase sympathetic nerve activity to the palm skin in the nonimmersed contralateral hand and reduce blood flow, reflecting on a decrease in skin surface temperature under a constant ambient environment. To test the hypothesis that gender might affect the contralateral vasoconstrictor response, we analyzed the spatiotemporal pattern of palm skin surface temperature during ice-water immersion for 10 min using thermography in eight males and eight females. As soon as the left hand was immersed in ice-water, palm skin temperature in the nonimmersed right hand quickly decreased in all subjects, particularly in the periphery of the digits and palm. The reduction in skin temperature was short-lasting in 63% of males and 38% of females, but it lasted throughout immersion in the remaining subjects. The average decrease in palm skin temperature was not significantly different between males and females, though it tended to be greater in males. The mean arterial blood pressure significantly increased and heart rate decreased during immersion in males, whereas no substantial cardiovascular changes were observed in females. Cold sensation was well coincident with the appearance of a reduction in the palm skin temperature. In consideration of all these results, we suggest that cutaneous cold stimuli increased skin sympathetic nerve activity in the nonimmersed hand and reduced skin blood flow. We also contend that gender difference in the contralateral vasoconstrictor response was denied because the time course and magnitude of the decrease in palm skin temperature were not different between males and females.
一只手浸入冰水所刺激的皮肤感受器会增加对侧未浸入手的手掌皮肤的交感神经活动，并减少血流量，这反映在恒定环境下皮肤表面温度的降低。为了验证性别可能影响对侧血管收缩反应这一假设，我们使用热成像技术分析了8名男性和8名女性在冰水浸泡10分钟期间手掌皮肤表面温度的时空模式。一旦左手浸入冰水中，所有受试者未浸入的右手手掌皮肤温度迅速下降，尤其是在手指和手掌的周边部位。63%的男性和38%的女性皮肤温度下降是短暂的，但在其余受试者中，这种下降持续了整个浸泡过程。男性和女性手掌皮肤温度的平均下降幅度没有显著差异，尽管男性的下降幅度往往更大。男性浸泡期间平均动脉血压显著升高，心率下降，而女性未观察到明显的心血管变化。冷觉与手掌皮肤温度下降的出现密切相关。综合所有这些结果，我们认为皮肤冷刺激会增加未浸入手的皮肤交感神经活动并减少皮肤血流量。我们还认为，对侧血管收缩反应不存在性别差异，因为男性和女性手掌皮肤温度下降的时间过程和幅度没有差异。
