Ciach Katarzyna, Preis Krzysztof, Swiatkowska-Freund Małgorzata, Wydra Dariusz
Katedra Perinatologii Klinika Poloinictwa AM w Gdańsku.
Ginekol Pol. 2007 May;78(5):400-4.
Whether or not to perform early or late amniocentesis remains questionable due to higher fetal loss and the rate of talipes equinovarus after early amniocentesis.
We have compared the course of pregnancy, delivery and the condition of the newborns in patients after early and late amniocentesis in the group of women who had undergone amniocentesis in the Department of Obstetrics of Medical University of Gdansk between the years 1996-2003.
Early amniocentesis was performed in 302 patients (55.9%), late amniocentesis in 302 patients (44.1%). Fetal loss occurred in 8 pregnancies (2.6%) after early amniocentesis and in 2 cases (0.8%) after late amniocentesis (P = 0.10). There was no statistically significant difference between early and late amniocentesis, comparing complications following the procedure in the first 3 weeks after amniocentesis: lower abdominal pain, spotting, bleeding, leakage of amniotic fluid. Mean duration of pregnancy in patients after early amniocentesis was 38.5 +/- 3.9 and 38.4 +/- 3.3 weeks in late amniocentesis group. There was no statistically significant difference between these groups in the type of delivery and premature delivery rate. Frequency of pneumonia and the respiratory infections in newborns were comparable in two groups (6.8% vs. 4.8%). There was only one case of talipes equnovarus in a fetus after late amniocentesis and one case of congenital dysplasia of the hip in a fetus after late amniocentesis, too. There were not any such defects in a group after early amniocentesis.
The type of amniocentesis--early or late--has not got any influence on the frequency of complicattions after amniocentesis.
由于早期羊膜穿刺术后胎儿丢失率较高以及马蹄内翻足发生率较高，早期或晚期进行羊膜穿刺术是否合适仍存在疑问。
我们比较了1996年至2003年间在格但斯克医科大学妇产科接受羊膜穿刺术的女性患者中，早期和晚期羊膜穿刺术后的妊娠过程、分娩情况及新生儿状况。
302例患者（55.9%）接受了早期羊膜穿刺术，302例患者（44.1%）接受了晚期羊膜穿刺术。早期羊膜穿刺术后8例妊娠（2.6%）发生胎儿丢失，晚期羊膜穿刺术后2例（0.8%）发生胎儿丢失（P = 0.10）。早期和晚期羊膜穿刺术之间在穿刺术后前三周的并发症（如下腹部疼痛、点滴出血、出血、羊水渗漏）方面无统计学显著差异。早期羊膜穿刺术后患者的平均妊娠时长为38.5±3.9周，晚期羊膜穿刺术组为38.4±3.3周。两组在分娩类型和早产率方面无统计学显著差异。两组新生儿肺炎和呼吸道感染的发生率相当（6.8%对4.8%）。晚期羊膜穿刺术后仅1例胎儿发生马蹄内翻足，晚期羊膜穿刺术后也有1例胎儿发生先天性髋关节发育不良。早期羊膜穿刺术组未出现此类缺陷。
羊膜穿刺术的类型（早期或晚期）对羊膜穿刺术后并发症的发生率没有任何影响。
