Ciach Katarzyna, Preis Krzysztof, Swiatkowska-Freund Małgorzata, Wydra Dariusz
Katedra Perinatologii Klinika Połoznictwa AM w Gdańsku.
Ginekol Pol. 2007 Jun;78(6):454-9.
The risk of fetal loss after amniocentesis is 0.2-1%. The aim of the study was to compare the course of pregnancy and delivery and the state of the newborn in patients after genetic amniocentesis and in the control group.
783 patients who underwent amniocentesis at the Department of Obstetrics of Medical University of Gdansk in 1996-2003 and 221 women who did not undergo amniocentesis.
Fetal loss occurred in 8 pregnancies (3.8%) after amniocentesis and in 12 (5.4%) p=0.37 in the control group. There was no significant statistical difference between the amniocentesis group and the control group comparing complications during pregnancy such as gestational diabetes mellitus, pregnancy induced hypertension, urinary tract infections. Cesarean section was more often performed in the amniocentesis group than in the control group, statistical difference p=0.003. Most often (28.09%) there was an elective cesarean section because of advanced maternal age without any obstetrician cause. The frequency of pneumonia, respiratory infections and congenital malformations in the first weeks of life was more frequent in the amniocetesis group.
Invasive prenatal diagnosis has no influence of the frequency of complications during pregnancy and delivery.
羊膜腔穿刺术后胎儿丢失的风险为0.2 - 1%。本研究的目的是比较基因羊膜腔穿刺术后患者与对照组的妊娠和分娩过程以及新生儿状况。
1996 - 2003年在格但斯克医科大学妇产科接受羊膜腔穿刺术的783例患者和221例未接受羊膜腔穿刺术的女性。
羊膜腔穿刺术后8例妊娠（3.8%）发生胎儿丢失，对照组为12例（5.4%），p = 0.37。在比较妊娠期间并发症如妊娠期糖尿病、妊娠高血压、尿路感染时，羊膜腔穿刺术组与对照组之间无显著统计学差异。羊膜腔穿刺术组剖宫产的实施频率高于对照组，统计学差异p = 0.003。最常见的情况（28.09%）是因产妇年龄较大而进行选择性剖宫产，无任何产科原因。羊膜腔穿刺术组出生后第一周内肺炎、呼吸道感染和先天性畸形的发生率更高。
侵入性产前诊断对妊娠和分娩期间并发症的发生率没有影响。
