Kornacki Jakub, Gozdziewicz Tomasz, Kwinecka Barbara, Skrzypczak Jana
Klinika Rozrodczości Katedry Ginekologii i Połoznictwa, Uniwersytetu Medycznego im. Karola Marcinkowskiego w Poznaniu.
Ginekol Pol. 2007 Jun;78(6):443-8.
Evaluation of the complications rate, as well as pregnancy outcome, in women who underwent early and mid-trimester amniocentesis.
The study was conducted among 454 patients, including 162 women after the procedure performed before 15 gestational week and 292 patients who underwent classic amniocentesis. All patients were hospitalized in Division of Reproduction of University of Medical Sciences in Poznan between 1999 and 2005. The analysis, based both on clinical observations and questionnaire sent to patients, concerned especially the frequency of following complications: miscarriage, premature rupture of membranes and club foot in newborns.
Total pregnancy loss rate due to amniocentesis amounted to 1.2% and 0.3% in early and mid-trimester amniocentesis, respectively, not reaching statistical significance. The frequency of club foot in newborns of mothers who underwent amniocentesis did not differ significantly between the groups, although it was four times higher in early amniocentesis group than in patients in whom mid-trimester amniocentesis had been performed.
The safety of early amniocentesis is comparable with safety of mid-trimester amniocentesis.
评估在孕早期和孕中期接受羊膜腔穿刺术的女性的并发症发生率以及妊娠结局。
该研究对454例患者进行，其中包括162例在妊娠15周前接受该手术的女性以及292例接受经典羊膜腔穿刺术的患者。所有患者于1999年至2005年期间在波兹南医科大学生殖科住院。基于临床观察和发给患者的问卷进行的分析，特别关注以下并发症的发生频率：流产、胎膜早破和新生儿马蹄内翻足。
因羊膜腔穿刺术导致的总妊娠丢失率在孕早期和孕中期羊膜腔穿刺术中分别为1.2%和0.3%，未达到统计学显著性。接受羊膜腔穿刺术的母亲所生新生儿马蹄内翻足的发生率在两组之间无显著差异，尽管孕早期羊膜腔穿刺术组比接受孕中期羊膜腔穿刺术的患者高出四倍。
孕早期羊膜腔穿刺术的安全性与孕中期羊膜腔穿刺术的安全性相当。
