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绿茶对心血管健康的作用机制及影响

Mechanisms and effects of green tea on cardiovascular health.

作者信息

Basu Arpita, Lucas Edralin A

机构信息

Department of Nutritional Sciences, 301 Human Environmental Sciences, Oklahoma State University, Stillwater, OK 74078-6141, USA.

出版信息

Nutr Rev. 2007 Aug;65(8 Pt 1):361-75. doi: 10.1301/nr.2007.aug.361-375.

DOI:10.1301/nr.2007.aug.361-375
PMID:17867370
Abstract

Green tea, rich in antioxidant and anti-inflammatory catechins, especially epigallocatechin gallate (EGCG), has been shown to reduce surrogate markers of atherosclerosis and lipid peroxidation, particularly LDL oxidation and malondialdehyde concentrations, in several in vitro, animal, and limited clinical studies. Epidemiological observations in Southeast Asian countries indicate an inverse correlation exists between habitual consumption of green tea beverages and the incidence of cardiovascular events. A few short-term clinical studies have reported its effects in attenuating biomarkers of oxidative stress and inflammation among smokers, and an ability to decrease postprandial lipemia in hypercholesterolemic subjects has also been suggested. However, further investigations are needed to confirm the potential role of green tea beverages and the safety of green tea supplements in reducing body fat, as well as other biomarkers of cardiovascular disease risks.

摘要

绿茶富含抗氧化和抗炎的儿茶素,尤其是表没食子儿茶素没食子酸酯(EGCG)。在一些体外、动物和有限的临床研究中,绿茶已被证明可降低动脉粥样硬化和脂质过氧化的替代指标,特别是低密度脂蛋白氧化和丙二醛浓度。东南亚国家的流行病学观察表明,经常饮用绿茶饮料与心血管事件的发生率呈负相关。一些短期临床研究报告了绿茶在减轻吸烟者氧化应激和炎症生物标志物方面的作用,并且也有人提出绿茶有降低高胆固醇血症患者餐后血脂的能力。然而,需要进一步研究来证实绿茶饮料在减少体脂以及心血管疾病风险的其他生物标志物方面的潜在作用,以及绿茶补充剂的安全性。

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