Kolossa-Gehring Marike, Becker Kerstin, Conrad André, Lüdecke Anja, Riedel Stefan, Seiwert Margarete, Schulz Christine, Szewzyk Regine
Umweltbundesamt (Federal Environment Agency), Corrensplatz 1, 14195 Berlin, Germany.
Int J Hyg Environ Health. 2007 Oct;210(5):535-40. doi: 10.1016/j.ijheh.2007.07.018. Epub 2007 Sep 17.
German Environmental Surveys (GerESs) are large scale population studies which have been carried out on adults in 1985/86, 1990/92 and 1998 and on children aged 6-14 years in 1990/92. GerES IV is the first survey focussing exclusively on children [Becker, K., Schulz, C., Babisch, W., Dürkop, J., Roskamp, E., Seiwert, M., Szewzyk, R., Ullrich, D., Seifert, B., 2005. German Environmental Survey for Children (GerES IV) 2003-2006. Pullut. Atmos. 188, 475-479]. GerES IV included a representative sample of 1790 children aged 3-14 of the participants of the National Health Interview and Examination Survey on Children and Adolescents. The primary goal of GerES IV is not only to analyse and document the extent, distribution and determinants of German children's exposure to environmental pollutants but to discover links between environmental exposure and health. Results will help develop preventive measures and advance further research. They might provide the basis for environmental and public health policy decisions. Precondition to achieve this task is a description of the data on exposures and the data on health outcomes. This work is currently performed at the Federal Environment Agency. First results show a remarkable decrease of the blood lead level of German children aged 6-14 years from 32.3 microg/l in 1990/92 (GerES II) to 16.3 microg/l in GerES IV which is the lowest mean lead concentration determined in German studies so far. None of the children had a value exceeding 100 microg/l. In GerES IV, the following health-related issues will be primarily examined: the relationship between sensitisation against mould spores and the occurrence of mould in households, irritation of eyes and respiratory system caused by formaldehyde, other aldehydes, or total volatile organic compounds (TVOC); the impact of non-occupational noise on hearing loss, stress and sleep disturbances, and the connection between contact allergies, nickel and scents. 9.5% of the children showed a sensitisation to at least one of the moulds examined (Penicillium (notatum) chrysogenum, Aspergillus versicolor, Wallemia sebi, Eurotium spp., Alternaria alternata). The most frequent sensitisation was against Penicillium chrysogenum. GerES IV might broaden the knowledge in terms of environmental causes of health outcomes. Children of smoking mothers showed higher mean cotinine concentrations than children living with a smoking father, regardless whether they smoked daily or occasionally. Results from the GerES IV pilot study showed a relation between environmental tobacco smoke (ETS) exposure and an increased susceptibility to infections and inflammations of the middle ear.
德国环境调查(GerESs)是针对成年人开展的大规模人群研究,分别于1985/86年、1990/92年和1998年进行,针对6 - 14岁儿童的研究于1990/92年开展。德国环境调查IV(GerES IV)是首次专门聚焦于儿童的调查[贝克尔,K.,舒尔茨,C.,巴比施,W.,迪尔科普,J.,罗斯坎普,E.,赛韦特,M.,泽维茨克,R.,乌尔里希,D.,塞弗特,B.,2005年。2003 - 2006年德国儿童环境调查(GerES IV)。《大气污染》。第188期,第475 - 479页]。GerES IV涵盖了1790名3 - 14岁儿童的代表性样本,这些儿童来自全国儿童和青少年健康访谈与检查调查的参与者。GerES IV的主要目标不仅是分析和记录德国儿童接触环境污染物的程度、分布及决定因素,还要发现环境暴露与健康之间的联系。研究结果将有助于制定预防措施并推动进一步研究。它们可能为环境和公共卫生政策决策提供依据。完成这项任务的前提是对暴露数据和健康结果数据进行描述。这项工作目前由联邦环境局开展。初步结果显示,德国6 - 14岁儿童的血铅水平显著下降,从1990/92年(GerES II)的32.3微克/升降至GerES IV中的16.3微克/升,这是德国研究中迄今测定的最低平均铅浓度。没有儿童的血铅值超过100微克/升。在GerES IV中,将主要研究以下与健康相关的问题:对霉菌孢子的致敏与家庭中霉菌出现之间的关系;甲醛、其他醛类或总挥发性有机化合物(TVOC)引起的眼睛和呼吸系统刺激;非职业性噪声对听力损失、压力和睡眠障碍的影响;以及接触性过敏、镍和香料之间的联系。9.5%的儿童对至少一种所检测的霉菌(产黄青霉、杂色曲霉、西氏瓦勒霉、曲霉菌属、链格孢)呈致敏状态。最常见的致敏是对产黄青霉。GerES IV可能会拓宽关于健康结果的环境成因方面的知识。母亲吸烟的儿童的平均可替宁浓度高于与吸烟父亲生活的儿童,无论父亲是每天吸烟还是偶尔吸烟。GerES IV试点研究的结果显示,环境烟草烟雾(ETS)暴露与中耳感染和炎症易感性增加之间存在关联。