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用于介入性磁共振成像的血管内导管的磁辅助远程控制(MARC)导向:偏转模型及设计启示

Magnetically-assisted remote control (MARC) steering of endovascular catheters for interventional MRI: a model for deflection and design implications.

作者信息

Settecase Fabio, Sussman Marshall S, Wilson Mark W, Hetts Steven, Arenson Ronald L, Malba Vincent, Bernhardt Anthony F, Kucharczyk Walter, Roberts Timothy P L

机构信息

Department of Medical Imaging and Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.

出版信息

Med Phys. 2007 Aug;34(8):3135-42. doi: 10.1118/1.2750963.

Abstract

Current applied to wire coils wound at the tip of an endovascular catheter can be used to remotely steer a catheter under magnetic resonance imaging guidance. In this study, we derive and validate an equation that characterizes the relationship between deflection and a number of physical factors: theta/sin(gamma-theta) = nIABL/EI(A) where theta is the deflection angle, n is the number of solenoidal turns, I is the current, A is the cross-sectional area of the catheter tip, B is the magnetic resonance (MR) scanner main magnetic field, L is the unconstrained catheter length, E is Young's Modulus for the catheter material, and I(A) is the area moment of inertia, and y is the initial angle between the catheter tip and B. Solenoids of 50, 100, or 150 turns were wound on 1.8 F and 5 F catheters. Varying currents were applied remotely using a DC power supply in the MRI control room. The distal catheter tip was suspended within a phantom at varying lengths. Images were obtained with a 1.5 T or a 3 T MR scanner using "real-time" MR pulse sequences. Deflection angles were measured on acquired images. Catheter bending stiffess was determined using a tensile testing apparatus and a stereomicroscope. Predicted relationships between deflection and various physical factors were observed (R2 = 0.98-0.99). The derived equation provides a framework for modeling of the behavior of the specialized catheter tip. Each physical factor studied has implications for catheter design and device implementation.

摘要

施加于缠绕在血管内导管尖端的线圈上的电流,可用于在磁共振成像引导下远程操控导管。在本研究中,我们推导并验证了一个表征偏转与若干物理因素之间关系的方程:θ/sin(γ - θ) = nIABL/EI(A),其中θ为偏转角,n为螺线管匝数,I为电流,A为导管尖端的横截面积,B为磁共振(MR)扫描仪主磁场,L为无约束导管长度,E为导管材料的杨氏模量,I(A)为面积惯性矩,γ为导管尖端与B之间的初始夹角。将50、100或150匝的螺线管缠绕在1.8F和5F的导管上。在MRI控制室中使用直流电源远程施加不同的电流。将导管远端尖端以不同长度悬浮在体模内。使用“实时”MR脉冲序列,通过1.5T或3T MR扫描仪获取图像。在采集的图像上测量偏转角。使用拉伸试验装置和立体显微镜测定导管的弯曲刚度。观察到了偏转与各种物理因素之间的预测关系(R2 = 0.98 - 0.99)。推导的方程为专门导管尖端行为的建模提供了一个框架。所研究的每个物理因素都对导管设计和设备实施有影响。

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